SCHEMBL8466940

SCHEMBL8466940

C=C(CC(C)(C)S(=O)(=O)O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 5/20 0.52
TET3 O43151 1/20 0.35
TET1 Q8NFU7 1/20 0.35
HMGCR P04035 1/20 0.31
CHRM1 P11229 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30
GRM1 Q13255 1/20 0.30
GRM2 Q14416 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30
ALDH1A1 P00352 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3112492 0.81 TDP1 (0.33) TET2
SCHEMBL8727012 0.77 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1ACYP2D6
SCHEMBL22812 0.74 TET2 (0.62) TET2TET3TET1HMGCRCHRM1
SCHEMBL346723 0.74 TET2 (0.62) TET2TET3TET1HMGCRCHRM1
Acrylamide SCHEMBL14635782 0.74 ALDH1A1 (0.38) TSHRALDH1A1
SCHEMBL18497006 0.72 TET2 (0.67) TET2TET3TET1HMGCRCHRM1
SCHEMBL10033928 0.72 ALDH1A1 (0.44) HMGCRCHRM1TBXA2RADRA1AALDH1A1
SCHEMBL4078779 0.72 TET2 (0.67) TET2TET3TET1HMGCRCHRM1
Sulfuric Acid SCHEMBL9101472 0.71 TET2 (0.44) TET2TET3TET1ALOX15HSD17B10
SCHEMBL2524423 0.70 TET2 (0.64) TET2TET3TET1HMGCRCHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990255-A FREE RADICAL BULK POLYMERIZATION PROCESS HAVING VINYL SULFUR OR PHOSPHORUS-CONTAINING ACIDS TO MODIFY THE VINYLAROMATIC POLYMER; MULTIMODAL, PREFERABLY BIMODAL, MOLECULAR WEIGHT DISTRIBUTION; KINETICS THE DOW CHEMICAL COMPANY (US) 1999-11-23 US disclosed
US-5962605-A BULK POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1999-10-05 US disclosed
EP-0797600-B1 HIGH MOLECULAR WEIGHT POLYSTYRENE PRODUCTION BY VINYLACID CATALYZED FREE RADICAL POLYMERIZATION DOW CHEMICAL CO (US) 1998-11-25 EP disclosed
EP-0797600-A1 HIGH MOLECULAR WEIGHT POLYSTYRENE PRODUCTION BY VINYLACID CATALYZED FREE RADICAL POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1997-10-01 EP disclosed
WO-1996018663-A1 HIGH MOLECULAR WEIGHT POLYSTYRENE PRODUCTION BY VINYLACID CATALYZED FREE RADICAL POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1996-06-20 WO disclosed