Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 9/20 | 0.52 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855451 | 1.00 | NOD1 (0.52) | NOD1SLC6A5EPHX1TLR2FOLH1 | |
| SCHEMBL5855445 | 1.00 | NOD1 (0.52) | NOD1SLC6A5EPHX1TLR2FOLH1 | |
| SCHEMBL8760314 | 0.99 | NOD1 (0.54) | NOD1SLC6A5EPHX1TLR2ITGB3 | |
| SCHEMBL9716662 | 0.95 | NOD1 (0.47) | NOD1SLC6A5FOLH1ITGB3ITGA2B | |
| SCHEMBL6688677 | 0.95 | NOD1 (0.47) | NOD1SLC6A5FOLH1ITGB3ITGA2B | |
| SCHEMBL6688681 | 0.95 | NOD1 (0.47) | NOD1SLC6A5FOLH1ITGB3ITGA2B | |
| SCHEMBL30915502 | 0.94 | SLC6A5 (0.56) | NOD1SLC6A5EPHX1TLR2FOLH1 | |
| SCHEMBL7803299 | 0.94 | SLC6A5 (0.56) | NOD1SLC6A5EPHX1TLR2FOLH1 | |
| SCHEMBL7804980 | 0.94 | SLC6A5 (0.56) | NOD1SLC6A5EPHX1TLR2FOLH1 | |
| SCHEMBL7797291 | 0.94 | SLC6A5 (0.56) | NOD1SLC6A5EPHX1TLR2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994361-A | ANTITUMOR, ANTICANCER AGENT | BIOCHEM PHARMA (CA) | 1999-11-30 | — | — | US | disclosed |
| EP-0766683-A1 | NOVEL SUBSTITUTED PURINYL DERIVATIVES WITH IMMUNOMODULATING ACTIVITY | BIOCHEM PHARMA INC (CA) | 1997-04-09 | — | — | EP | disclosed |