SCHEMBL846725

SCHEMBL846725

c1ccc(CN(Cc2ccccn2)C(c2ccccn2)c2ccccn2)nc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
LIN28A Q9H9Z2 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
KCNA5 P22460 3/20 0.46
KCNH2 Q12809 1/20 0.46
TSHR P16473 2/20 0.44
KMT2A Q03164 1/20 0.44
CYP2D6 P10635 1/20 0.44
KCNE1 P15382 1/20 0.44
CXCR4 P61073 2/20 0.42
HRH1 P35367 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30195630 1.00 MAPT (0.53) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL18301494 0.93 MAPT (0.55) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL18301484 0.92 CYP1A2 (0.48) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL29496728 0.92 CYP1A2 (0.48) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL5556120 0.90 MAPT (0.51) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL23111326 0.87 KCNA5 (0.46) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL15483829 0.87 CXCR4 (0.46) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL15483563 0.84 CXCR4 (0.46) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL15483626 0.83 CXCR4 (0.43) MAPTSMN1; SMN2LIN28ATDP1KCNA5
SCHEMBL5556661 0.82 CXCR4 (0.62) MAPTSMN1; SMN2LIN28ATDP1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250059379-A1 PAINTS CONTAINING DRIERS BASED ON VANADIUM COMPOUNDS BEARING VARIOUS ACID ANIONS BORCHERS GMBH (DE) 2025-02-20 US claimed
CN-119303554-A Preparation method and application of host-guest composite material based on non-heme iron complex and UiO-66 西北工业大学深圳研究院 2025-01-14 CN claimed
CN-119192601-A Main and guest composite material based on metal organic framework material and N4Py high-valence mononuclear iron complex, and preparation method and application thereof 西北工业大学 2024-12-27 CN claimed
US-20240417590-A1 PROCESS FOR IMPROVING RESIN PERFORMANCE USING LEWIS ACIDS BORCHERS GMBH (DE) 2024-12-19 US claimed
US-20240368378-A1 PROCESS FOR IMPROVING RESIN PERFORMANCE BORCHERS GMBH (DE) 2024-11-07 US claimed
EP-4453106-A1 PAINTS CONTAINING DRIERS BASED ON VANADIUM COMPOUNDS BEARING VARIOUS ACID ANIONS Borchers GmbH (DE) 2024-10-30 EP claimed
CN-118647679-A Coating containing a drier based on vanadium compounds with various acid anions 博奇斯有限公司 2024-09-13 CN claimed
EP-4408942-A1 PROCESS FOR IMPROVING RESIN PERFORMANCE USING LEWIS ACIDS Borchers GmbH (DE) 2024-08-07 EP claimed
EP-4396298-A1 PROCESS FOR IMPROVING RESIN PERFORMANCE Borchers GmbH (DE) 2024-07-10 EP claimed
CN-118215715-A Method for improving resin properties 博奇斯有限公司 2024-06-18 CN claimed
US-20100112393-A1 FUEL CELLS ACAL ENERGY LIMITED (GB) 2010-05-06 US claimed
US-20100112388-A1 FUEL CELLS ACAL ENERGY LIMITED (GB) 2010-05-06 US claimed
US-20090253833-A1 Liquid Hardening OMG UK TECHNOLOGY LTD (GB) 2009-10-08 US claimed
EP-1341893-B1 ENZYMATIC DETERGENT COMPOSITIONS UNILEVER NV (NL) 2007-05-02 EP claimed
US-20030050211-A1 Enzymatic detergent compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2003-03-13 US claimed
US-20020137654-A1 Enzymatic detergent compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2002-09-26 US claimed
EP-0765381-B1 BLEACH ACTIVATION UNILEVER NV (NL) 1999-08-11 EP claimed
EP-0765381-A1 BLEACH ACTIVATION UNILEVER N.V. (NL) 1997-04-02 EP claimed
US-5580485-A IRON-COMPLEXES; OXIDATION CATALYSTS LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) 1996-12-03 US claimed
WO-1995034628-A1 BLEACH ACTIVATION UNILEVER N.V. (NL) 1995-12-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100112393-A1 FUEL CELLS PCK2, CS, FECH MAPT 4341/4885SMN1; SMN2 3999/4885LIN28A 4829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.