SCHEMBL8467304

SCHEMBL8467304

CC(O)COC(=O)c1cccc(C(=O)OCC(C)O)c1

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 14/20 0.55
ADRB1 P08588 14/20 0.55
ADRB3 P13945 14/20 0.55
ALDH1A1 P00352 2/20 0.55
TSHR P16473 1/20 0.46
PTPN1 P18031 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8203711 0.93 ALDH1A1 (0.53) ADRB2ADRB1ADRB3ALDH1A1
SCHEMBL1926524 0.87 ALDH1A1 (0.72) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL524376 0.87 ALDH1A1 (0.72) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL109308 0.87 ALDH1A1 (0.61) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL28213786 0.85 ADRB2 (0.51) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL4762261 0.85 ALDH1A1 (0.58) ADRB2ADRB1ADRB3ALDH1A1PTPN1
SCHEMBL441479 0.84 MAPT (0.58) ADRB2ADRB1ADRB3ALDH1A1
SCHEMBL28859685 0.84 ADRB2 (0.50) ADRB2ADRB1ADRB3ALDH1A1TSHR
SCHEMBL11692683 0.83 ALDH1A1 (0.43) ADRB2ADRB1ADRB3ALDH1A1
Maleic Anhydride SCHEMBL9176602 0.83 ALDH1A1 (0.43) ADRB2ADRB1ADRB3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112833187-A High-temperature-resistant piston rod sealing system of middle-high-end excavator 上海唯万密封科技股份有限公司 2021-05-25 CN claimed
CN-115806658-B Polyester and preparation method and application thereof 珠海万通化工有限公司 2023-11-03 CN disclosed
CN-112833187-B High temperature resistant type piston rod sealing system of middle-high end excavator 上海唯万密封科技股份有限公司 2023-04-25 CN disclosed
CN-112833187-A High-temperature-resistant piston rod sealing system of middle-high-end excavator 上海唯万密封科技股份有限公司 2021-05-25 CN disclosed
EP-0930327-A2 Aromatic polyol end-capped unsaturated polyetherester resins and resin compositions containing the same having improved chemical and/or water resistance Cook Composites and Polymers Company (US) 1999-07-21 EP disclosed
EP-0172610-B1 Polyurethane prepolymers and elastomers GORE & ASS (US) 1994-07-13 EP disclosed
EP-0283172-B1 LOAD-BEARING ARTICLE HAVING SURFACE LUBRICITY ICI AMERICAS INC. (US) 1992-04-22 EP disclosed
EP-0283172-A1 Load-bearing article having surface lubricity ICI AMERICAS INC. (US) 1988-09-21 EP disclosed
US-4766194-A ISOCYANATE-REACTIVE LUBRICANT INCORPORATED INTO POLYURETHANE MOLDING ICI AMERICAS INC. (US) 1988-08-23 US disclosed
CN-85104738-A Polyurethane prepolymers and elastomerics 1986-12-24 CN disclosed
EP-0172610-A1 Polyurethane prepolymers and elastomers W.L. GORE & ASSOCIATES, INC. (US) 1986-02-26 EP disclosed
US-4045527-A MIXING POLYTETRAMETHYLENE GLYCOL RESIN PREPOLYMER WITH A DIISOCYANATE, A METAL SALT CURING CATALYST, AND A TETRAALKANOL AMINE CURING AGENT HITCO (US) 1977-08-30 US disclosed