Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 10/20 | 0.86 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.86 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.86 |
| ▸ | MMP2 | P08253 | 1/20 | 0.86 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.86 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | PTGES | O14684 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.56 |
| ▸ | OSBP | P22059 | 1/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467358 | 1.00 | AKR1C3 (0.86) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL2138507 | 0.92 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL7128580 | 0.92 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| Artepillin SCHEMBL1229229 | 0.92 | AKR1C3 (1.00) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL25890163 | 0.88 | AKR1C3 (0.91) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL26422962 | 0.88 | AKR1C3 (0.91) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL23742688 | 0.85 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL11036838 | 0.85 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL29574915 | 0.85 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 | |
| SCHEMBL23742687 | 0.85 | AKR1C3 (0.84) | AKR1C3AKR1B10AKR1B1MMP2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11349526-A | — | — | None | — | — | JP | disclosed |
| CN-117794534-A | Compositions for modulating cortisol homeostasis and improving sleep quality and methods of use and preparation thereof | 尤尼根公司 | 2024-03-29 | — | — | CN | disclosed |
| JP-H11349526-A | NEW COMPOUND OR ITS PHARMACOLOGICALLY ACCEPTABLE SALT AND ANTIOXIDANT CONTAINING THE SAME AS ACTIVE INGREDIENT | OYO SEIKAGAKU KENKYUSHO | 1999-12-21 | — | — | JP | disclosed |