SCHEMBL8467448

SCHEMBL8467448

CN(C(=S)SSC(=S)N(C)C1CCCCC1)C1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 3/20 1.00
PHGDH O43175 2/20 1.00
FAAH O00519 2/20 1.00
ALDH1A1 P00352 5/20 0.43
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
LMNA P02545 3/20 0.40
MAPT P10636 3/20 0.40
HTT P42858 2/20 0.40
CYP3A4 P08684 2/20 0.40
KDM4E B2RXH2 1/20 0.40
JAK2 O60674 1/20 0.40
BBOX1 O75936 1/20 0.40
TP53 P04637 1/20 0.40
ALDH2 P05091 1/20 0.40
HSP90AA1 P07900 1/20 0.40
FBP1 P09467 1/20 0.40
PKM P14618 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8468236 0.76 PHGDH (1.00) MGLLPHGDHFAAHALDH1A1MEN1
Hydrochloric Acid SCHEMBL11632374 0.74 PHGDH (0.59) MGLLPHGDHFAAHALDH1A1MEN1
Zinc Ion SCHEMBL2923805 0.74 PHGDH (0.59) MGLLPHGDHFAAHALDH1A1MEN1
SCHEMBL11632370 0.74 PHGDH (0.59) MGLLPHGDHFAAHALDH1A1MEN1
SCHEMBL27571128 0.74 PHGDH (0.59) MGLLPHGDHFAAHALDH1A1MEN1
SCHEMBL11750896 0.74 PHGDH (0.59) MGLLPHGDHFAAHALDH1A1MEN1
SCHEMBL13696652 0.74 PHGDH (0.59) MGLLPHGDHFAAHALDH1A1MEN1
SCHEMBL9666957 0.73 PHGDH (0.57) MGLLPHGDHFAAHALDH1A1MEN1
SCHEMBL11612504 0.72 PHGDH (0.61) MGLLPHGDHFAAHALDH1A1MEN1
SCHEMBL31364231 0.72 FAAH (0.54) MGLLPHGDHFAAHALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805281-B1 ACRYLIC RUBBER AND CROSSLINKABLE COMPOSITION THEREOF UNIMATEC CO LTD (JP) 2025-03-12 EP disclosed
US-11795251-B2 Acrylic rubber and crosslinkable composition thereof UNIMATEC CO., LTD. (JP) 2023-10-24 US disclosed
CN-112041356-B Acrylic rubber and crosslinkable composition thereof 优迈特株式会社 2022-06-10 CN disclosed
US-20210155729-A1 ACRYLIC RUBBER AND CROSSLINKABLE COMPOSITION THEREOF Unimatec., Ltd. (JP) 2021-05-27 US disclosed
EP-3805281-A1 ACRYLIC RUBBER AND CROSSLINKABLE COMPOSITION THEREOF Unimatec Co., Ltd. (JP) 2021-04-14 EP disclosed
CN-109384702-B Preparation method of N-dithiocarbamate indole compound 温州医科大学 2020-08-25 CN disclosed
US-5965640-A A CROSSLINKABLE ACRYLIC RUBBER COMPRISES A HALOGEN CONTAINING ACRYLIC RUBBER, A TRIAZINE THIOL, DITHIOCARBAMINE ACID DERIVATIVE OR THIURAM SULFIDE OR BOTH, AN AROMATIC CARBOXYLIC ACID OR AN ACID ANHYDRIDE, WHITE FILLER AND SILANE COUPLER JSR CORPORATION (JP) 1999-10-12 US disclosed
EP-0811659-A2 Acrylic rubber composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-10 EP disclosed
US-4468526-A Process for the preparation of thiuram disulfides AKZONA INCORPORATED (US) 1984-08-28 US disclosed
US-4459424-A SECONDARY AMINE, CARBON DISULFIDE, METAL CONTAINING CATALYST AKZONA INCORPORATED (US) 1984-07-10 US disclosed