SCHEMBL8468236

SCHEMBL8468236

S=C(SSC(=S)N(C1CCCCC1)C1CCCCC1)N(C1CCCCC1)C1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 4/20 1.00
MGLL Q99685 7/20 0.61
FAAH O00519 2/20 0.61
ALDH1A1 P00352 4/20 0.41
TP53 P04637 3/20 0.33
CYP3A4 P08684 3/20 0.33
LMNA P02545 3/20 0.33
ALOX15 P16050 3/20 0.33
ALOX12 P18054 3/20 0.33
KMT2A Q03164 3/20 0.33
ALDH2 P05091 2/20 0.33
HSP90AA1 P07900 2/20 0.33
FBP1 P09467 2/20 0.33
MAPT P10636 2/20 0.33
PKM P14618 2/20 0.33
HPGD P15428 2/20 0.33
LOX P28300 2/20 0.33
HTT P42858 2/20 0.33
LOXL3 P58215 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6830758 0.89 PHGDH (0.80) PHGDHMGLLFAAHALDH1A1
SCHEMBL11591673 0.81 PHGDH (0.68) PHGDHMGLLFAAHALDH1A1TP53
SCHEMBL9871978 0.81 PHGDH (0.68) PHGDHMGLLFAAHALDH1A1LMNA
SCHEMBL11569028 0.78 PHGDH (0.63) PHGDHMGLLFAAHALDH1A1MAPT
SCHEMBL1001644 0.77 PHGDH (0.62) PHGDHMGLLFAAHALDH1A1TP53
SCHEMBL11824520 0.76 PHGDH (0.59) PHGDHMGLLFAAHALDH1A1CYP3A4
SCHEMBL8467448 0.76 MGLL (1.00) PHGDHMGLLFAAHALDH1A1TP53
SCHEMBL11612504 0.76 PHGDH (0.61) PHGDHMGLLFAAHALDH1A1TP53
SCHEMBL9871394 0.76 PHGDH (0.61) PHGDHMGLLFAAHALDH1A1TP53
SCHEMBL1426473 0.76 PHGDH (0.61) PHGDHMGLLFAAHALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805281-B1 ACRYLIC RUBBER AND CROSSLINKABLE COMPOSITION THEREOF UNIMATEC CO LTD (JP) 2025-03-12 EP disclosed
US-11795251-B2 Acrylic rubber and crosslinkable composition thereof UNIMATEC CO., LTD. (JP) 2023-10-24 US disclosed
CN-112041356-B Acrylic rubber and crosslinkable composition thereof 优迈特株式会社 2022-06-10 CN disclosed
US-20210155729-A1 ACRYLIC RUBBER AND CROSSLINKABLE COMPOSITION THEREOF Unimatec., Ltd. (JP) 2021-05-27 US disclosed
EP-3805281-A1 ACRYLIC RUBBER AND CROSSLINKABLE COMPOSITION THEREOF Unimatec Co., Ltd. (JP) 2021-04-14 EP disclosed
CN-112041356-A Acrylic rubber and crosslinkable composition thereof 优迈特株式会社 2020-12-04 CN disclosed
EP-2792479-B1 RUBBER/RESIN COMPOSITE HOSE YOKOHAMA RUBBER CO LTD (JP) 2016-11-02 EP disclosed
US-20150000781-A1 Rubber/Resin Composite Hose THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-01-01 US disclosed
EP-2792479-A1 RUBBER/RESIN COMPOSITE HOSE The Yokohama Rubber Co., Ltd. (JP) 2014-10-22 EP disclosed
US-5965640-A A CROSSLINKABLE ACRYLIC RUBBER COMPRISES A HALOGEN CONTAINING ACRYLIC RUBBER, A TRIAZINE THIOL, DITHIOCARBAMINE ACID DERIVATIVE OR THIURAM SULFIDE OR BOTH, AN AROMATIC CARBOXYLIC ACID OR AN ACID ANHYDRIDE, WHITE FILLER AND SILANE COUPLER JSR CORPORATION (JP) 1999-10-12 US disclosed
EP-0811659-A2 Acrylic rubber composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-10 EP disclosed
EP-0006698-B1 CURABLE POLYSULFIDE POLYMER COMPOSITION AND PROCESS FOR THE PREPARATION OF A SHAPED ARTICLE THEREFROM THIOKOL CORPORATION (US) 1983-05-04 EP disclosed
US-4314920-A Polysulfide rubbers suitable for hot application THIOKOL CORPORATION (US) 1982-02-09 US disclosed
US-4263078-A HEATING, EXTRUDING WITH SULFUR-CONTAINING ACCELERATORS THIOKOL CORPORATION (US) 1981-04-21 US disclosed
US-4006140-A AGING RESISTANCE IMPROVERS FOR VULCANIZABLE RUBBERS THE B. F. GOODRICH COMPANY (US) 1977-02-01 US disclosed