Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6729364 | 0.86 | TSHR (0.48) | MEN1KMT2A | |
| SCHEMBL17807999 | 0.86 | TSHR (0.48) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL965649 | 0.84 | TSHR (0.47) | MEN1KMT2A | |
| SCHEMBL19090603 | 0.82 | SIGMAR1 (0.50) | SIGMAR1L3MBTL1MEN1KMT2AMAOA | |
| SCHEMBL108633 | 0.82 | LMNA (0.54) | SIGMAR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL30514257 | 0.80 | LMNA (0.53) | SIGMAR1MEN1KMT2A | |
| SCHEMBL8468315 | 0.79 | MAOB (0.50) | SIGMAR1MAOA | |
| SCHEMBL918838 | 0.79 | SIGMAR1 (0.44) | SIGMAR1L3MBTL1MEN1KMT2A | |
| SCHEMBL1678945 | 0.78 | GRIK1 (0.54) | MEN1KMT2A | |
| SCHEMBL1487691 | 0.78 | MAOB (0.48) | SIGMAR1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869471-A | Methods for the treatment of arthritis using phosphonates and NSAIDS | THE PROCTOR & GAMBLE COMPANY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5824661-A | TREATMENT OF OSTEOPOROSIS, OSTEOARTHRITIS, RHEUMATOID ARTHRITIS | THE PROCTER & GAMBLE COMPANY (US) | 1998-10-20 | — | — | US | disclosed |
| EP-0642519-A1 | SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS (US) | 1995-03-15 | — | — | EP | disclosed |
| WO-1993024496-A1 | SULFUR-CONTAINING PHOSPONATE COMPOUNDS FOR TREATING ABNORMAL CALCIUM AND PHOSPHATE METABOLISM | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1993-12-09 | — | — | WO | disclosed |