SCHEMBL8467883

SCHEMBL8467883

Cc1ccc(OP(O)(=S)S)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.38
TP53 P04637 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HPGD P15428 2/20 0.37
ACHE P22303 1/20 0.36
LMNA P02545 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HSP90AA1 P07900 1/20 0.35
UBE2N P61088 1/20 0.35
MRGPRX4 Q96LA9 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467688 0.85 TP53 (0.40) L3MBTL1TP53TDP1HPGDACHE
SCHEMBL4388731 0.85 ACHE (0.39) L3MBTL1TP53TDP1HPGDACHE
SCHEMBL8467715 0.85 ACHE (0.39) L3MBTL1TP53TDP1HPGDACHE
SCHEMBL8469163 0.85 TP53 (0.40) L3MBTL1TP53TDP1HPGDACHE
SCHEMBL9003233 0.81 L3MBTL1 (0.38) L3MBTL1TP53TDP1HPGDACHE
Zinc Ion SCHEMBL2982380 0.81 ACHE (0.36) L3MBTL1TP53TDP1HPGDACHE
SCHEMBL258349 0.80 ACHE (0.41) L3MBTL1TP53TDP1HPGDACHE
SCHEMBL11420438 0.79 L3MBTL1 (0.36) L3MBTL1TP53TDP1HPGDACHE
SCHEMBL9003240 0.79 L3MBTL1 (0.36) L3MBTL1TP53TDP1HPGDACHE
SCHEMBL11435378 0.79 ACHE (0.34) L3MBTL1TP53TDP1HPGDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed