SCHEMBL8467924

SCHEMBL8467924

CCCC/C=C/CCN1C(=O)CCC1=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.70
FAAH O00519 6/20 0.70
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
DRD2 P14416 1/20 0.37
CHRM3 P20309 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
KMT2A Q03164 1/20 0.37
TRPV1 Q8NER1 2/20 0.36
F7 P08709 1/20 0.36
F3 P13726 1/20 0.36
TSHR P16473 2/20 0.34
ALDH1A1 P00352 1/20 0.34
PTGS1 P23219 2/20 0.33
PTGS2 P35354 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8205784 0.93 FAAH (0.76) MGLLFAAHCHRM1MEN1POLB
SCHEMBL10693932 0.93 FAAH (0.76) MGLLFAAHCHRM1MEN1POLB
SCHEMBL9515335 0.93 FAAH (0.76) MGLLFAAHCHRM1MEN1POLB
SCHEMBL1060198 0.93 FAAH (0.76) MGLLFAAHCHRM1MEN1POLB
SCHEMBL734670 0.85 FAAH (0.87) MGLLFAAHCHRM1POLBKMT2A
SCHEMBL11605800 0.79 FAAH (0.68) MGLLFAAHCHRM1MEN1POLB
SCHEMBL5963786 0.79 MGLL (0.61) MGLLFAAHCHRM2CHRM4CHRM5
SCHEMBL8993888 0.78 FAAH (0.66) MGLLFAAHCHRM1MEN1POLB
SCHEMBL11605602 0.78 FAAH (0.66) MGLLFAAHCHRM1MEN1POLB
SCHEMBL8993908 0.78 FAAH (0.66) MGLLFAAHCHRM1MEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
EP-0448207-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1993-12-15 EP disclosed
US-5225093-A Metal free ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-07-06 US disclosed
US-5176840-A Succinimide ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-01-05 US disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed
EP-0448207-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-09-25 EP disclosed