SCHEMBL8468296

SCHEMBL8468296

COCc1[c]cccc1COC

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
ALOX12 P18054 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PRKCG P05129 1/20 0.31
MAPT P10636 1/20 0.31
PRKCA P17252 1/20 0.31
APEX1 P27695 1/20 0.31
RECQL P46063 1/20 0.31
PRKCE Q02156 1/20 0.31
KMT2A Q03164 1/20 0.31
MYLK Q15746 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
IDO1 P14902 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8878410 0.85 ADRA2A (0.32)
SCHEMBL6282544 0.79 TSHR (0.31)
SCHEMBL10530516 0.78
SCHEMBL16719360 0.78 TP53 (0.34) KDM4ENPC1ALOX12HTTRAB9A
SCHEMBL6203845 0.78 CA1 (0.41) KDM4EALOX12HTTALDH1A1MAPT
SCHEMBL6204663 0.78 IDO1 (0.31) TDP1IDO1
SCHEMBL11792740 0.72
SCHEMBL648491 0.71 IDO1 (0.44) PDK2KDM4ENPC1ALOX12HTT
SCHEMBL6736553 0.70 ABL1 (0.45) NPC1RAB9AMAPT
SCHEMBL8471081 0.69 PDK2 (0.37) PDK2HTTNPSR1MEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5945501-A Epoxy resin compositions including novel phenol novolak condensates produced from bis(methoxymethyl)biphenyls UBE INDUSTRIES, LTD. (JP) 1999-08-31 US disclosed
US-5612442-A Phenol novolak condensate and bis(methoxymethyl)biphenyl for production thereof UBE INDUSTRIES, LTD. (JP) 1997-03-18 US disclosed