Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | MARK3 | P27448 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | FRK | P42685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468310 | 0.88 | CRHR1 (0.34) | PDK2RAPGEF4CRHR1CYP1A2CYP2A6 | |
| SCHEMBL11336681 | 0.88 | MYC (0.41) | PDK2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL10605861 | 0.80 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1884447 | 0.79 | PDK2 (0.37) | PDK2RAPGEF4CRHR1MEN1KMT2A | |
| SCHEMBL1884446 | 0.78 | CRHR1 (0.36) | PDK2RAPGEF4CRHR1MEN1KMT2A | |
| SCHEMBL2449658 | 0.76 | PDK2 (0.33) | PDK2CRHR1MEN1KMT2AALDH1A1 | |
| SCHEMBL10604025 | 0.76 | — | — | |
| SCHEMBL2679926 | 0.76 | PDK2 (0.36) | PDK2RAPGEF4CRHR1MEN1KMT2A | |
| SCHEMBL2449657 | 0.75 | MEN1 (0.34) | CRHR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11336680 | 0.75 | MYC (0.38) | PDK2MEN1KMT2ACYP1A2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090524-B1 | THERMAL OXIDATION STABILIZER COMPOSED OF PHOSPHITE DERIVATIVES OF AN ALCOHOL AND PPE MONOMER STILL BOTTOMS, AND PPE COMPOSITIONS CONTAINING SAID PHOSPHITES | GENERAL ELECTRIC COMPANY (US) | 1986-10-29 | — | — | EP | claimed |
| EP-0639620-B1 | Thermoplastic compositions containing polyphenylene ether resin | GEN ELECTRIC (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5397822-A | Thermoplastic compositions containing polyphenylene ether resin and characterized by improved elongation and flexibility employing a blend of multiblock copolymers | GENERAL ELECTRIC COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0639620-A2 | Thermoplastic compositions containing polyphenylene ether resin | GENERAL ELECTRIC COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5364898-A | Dielectric articles with polymer coatings | GENERAL ELECTRIC COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0413972-B1 | Improved thermoplastic compositions which contain polyolefins and polyphenylene ethers, and articles made therefrom | GEN ELECTRIC (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5294655-A | Including a phenylsiloxane fluid and a flexibilizing elastomeric hydrogenated block polymer containing an ethylene/butylene block and a vinyl aromatic block | GENERAL ELECTRIC COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0467113-A1 | Thermoplastic compositions containing polyphenylene ether resin and characterized by improved elongation and flexibility | GENERAL ELECTRIC COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0413972-A2 | Improved thermoplastic compositions which contain polyolefins and polyphenylene ethers, and articles made therefrom | GENERAL ELECTRIC COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4822837-A | CONTAINING OXIDIZED WAXES | GENERAL ELECTRIC COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0164767-B1 | POLYMER MIXTURE COMPRISING A POLYPHENYLENE ETHER AND A POLYAMIDE | GENERAL ELECTRIC COMPANY (US) | 1988-09-07 | — | — | EP | disclosed |
| US-4659760-A | WITH AN OXIDIZED WAX | GENERAL ELECTRIC COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0164767-A2 | Polymer mixture comprising a polyphenylene ether and a polyamide | GENERAL ELECTRIC COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4276233-A | THERMAL STABILIZERS FOR POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 1981-06-30 | — | — | US | disclosed |