Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468313 | 0.88 | PDK2 (0.35) | CRHR1PDK2CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL11336680 | 0.87 | MYC (0.38) | PDK2CYP1A2CYP2A6ALDH1A1MAPT | |
| SCHEMBL1884446 | 0.79 | CRHR1 (0.36) | CRHR1PDK2CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL10605858 | 0.78 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1884447 | 0.77 | PDK2 (0.37) | CRHR1PDK2CYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL2449657 | 0.77 | MEN1 (0.34) | CRHR1ALDH1A1MAPTHPGDMAPK1 | |
| SCHEMBL11336681 | 0.75 | MYC (0.41) | PDK2ALDH1A1MAPTLMNAHTT | |
| SCHEMBL2449658 | 0.74 | PDK2 (0.33) | CRHR1PDK2ALDH1A1MAPTMAPK1 | |
| SCHEMBL10604022 | 0.73 | MAPK1 (0.32) | MAPTMAPK1LMNASMN1; SMN2HTT | |
| SCHEMBL20560117 | 0.72 | PDK2 (0.33) | PDK2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639620-B1 | Thermoplastic compositions containing polyphenylene ether resin | GEN ELECTRIC (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5397822-A | Thermoplastic compositions containing polyphenylene ether resin and characterized by improved elongation and flexibility employing a blend of multiblock copolymers | GENERAL ELECTRIC COMPANY (US) | 1995-03-14 | — | — | US | disclosed |
| EP-0639620-A2 | Thermoplastic compositions containing polyphenylene ether resin | GENERAL ELECTRIC COMPANY (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5364898-A | Dielectric articles with polymer coatings | GENERAL ELECTRIC COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0413972-B1 | Improved thermoplastic compositions which contain polyolefins and polyphenylene ethers, and articles made therefrom | GEN ELECTRIC (US) | 1994-10-12 | — | — | EP | disclosed |
| US-5294655-A | Including a phenylsiloxane fluid and a flexibilizing elastomeric hydrogenated block polymer containing an ethylene/butylene block and a vinyl aromatic block | GENERAL ELECTRIC COMPANY (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0467113-A1 | Thermoplastic compositions containing polyphenylene ether resin and characterized by improved elongation and flexibility | GENERAL ELECTRIC COMPANY (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0413972-A2 | Improved thermoplastic compositions which contain polyolefins and polyphenylene ethers, and articles made therefrom | GENERAL ELECTRIC COMPANY (US) | 1991-02-27 | — | — | EP | disclosed |
| US-4822837-A | CONTAINING OXIDIZED WAXES | GENERAL ELECTRIC COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| EP-0164767-B1 | POLYMER MIXTURE COMPRISING A POLYPHENYLENE ETHER AND A POLYAMIDE | GENERAL ELECTRIC COMPANY (US) | 1988-09-07 | — | — | EP | disclosed |
| US-4659760-A | WITH AN OXIDIZED WAX | GENERAL ELECTRIC COMPANY (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0164767-A2 | Polymer mixture comprising a polyphenylene ether and a polyamide | GENERAL ELECTRIC COMPANY (US) | 1985-12-18 | — | — | EP | disclosed |
| US-4276233-A | THERMAL STABILIZERS FOR POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 1981-06-30 | — | — | US | disclosed |