SCHEMBL8468352

SCHEMBL8468352

O=C(O)CNc1ccc(CO)cc1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 9/20 0.43
FFAR4 Q5NUL3 3/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
RAB9A P51151 1/20 0.39
GFER P55789 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
POLB P06746 1/20 0.39
EGLN1 Q9GZT9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5692310 0.87 ALDH1A1 (0.44) FFAR1FFAR4ALDH1A1RAB9ASMN1; SMN2
SCHEMBL10952623 0.84 FFAR1 (0.49) FFAR1FFAR4TDP1
SCHEMBL13611310 0.83 FFAR1 (0.59) FFAR1TSHRALDH1A1RAB9AGFER
SCHEMBL3814850 0.82 TPSAB1 (0.46) FFAR1FFAR4TSHRSMN1; SMN2
Hydrochloric Acid SCHEMBL11841695 0.82 CA1 (0.44) FFAR1FFAR4RAB9AGFERSMN1; SMN2
SCHEMBL11622277 0.82 CA1 (0.44) FFAR1FFAR4RAB9AGFERSMN1; SMN2
SCHEMBL10955013 0.82 ALDH1A1 (0.52) FFAR1ALDH1A1RAB9APOLBEGLN1
SCHEMBL5954234 0.80 FFAR1 (0.53) FFAR1FFAR4RAB9AGFERSMN1; SMN2
SCHEMBL22873353 0.80 TSHR (0.43) TSHRALDH1A1POLB
SCHEMBL6167395 0.79 ESR1 (0.52) FFAR1FFAR4ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3972919-A CHEMICAL INTERMEDIATE FOR ANTIBIOTICS SMITHKLINE CORPORATION (US) 1976-08-03 US claimed
JP-54125628-A None JP disclosed
US-7635181-B2 Ink for ink jet-recording curable through irradiation with a radioactive ray and method for preparing lithographic printing plates using the same FUJIFILM CORPORATION (JP) 2009-12-22 US disclosed
US-7582410-B2 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2009-09-01 US disclosed
US-7416835-B2 Polymerizable composition FUJIFILM CORPORATION (JP) 2008-08-26 US disclosed
US-20080038663-A1 butadiene-styrene copolymer binder and a compound which undergoes decarboxylation due to heat, generates carbon dioxide gas, assists thermal decomposition of the coexisting binder polymer; high engraving sensitivity with low laser energy; forming flexographic printing plate FUJIFILM CORPORATION (JP) 2008-02-14 US disclosed
EP-0809490-A4 USE OF LCK SH2 SPECIFIC COMPOUNDS TO TREAT AUTOIMMUNE DISEASES AND ALLOGRAFT REJECTION SMITHKLINE BEECHAM CORP (US) 1999-10-20 EP disclosed
EP-0871436-A4 USE OF Stat 6 SH2 DOMAIN SPECIFIC COMPOUNDS TO TREAT ALLERGIC REACTIONS SMITHKLINE BEECHAM CORP (US) 1999-10-20 EP disclosed
EP-0835104-A4 USE OF STAT 5 SH2 DOMAIN SPECIFIC COMPOUNDS TO ENHANCE ERYTHROPOIESIS SMITHKLINE BEECHAM CORP (US) 1999-10-20 EP disclosed
EP-0871436-A1 USE OF Stat 6 SH2 DOMAIN SPECIFIC COMPOUNDS TO TREAT ALLERGIC REACTIONS SMITHKLINE BEECHAM CORPORATION (US) 1998-10-21 EP disclosed
US-4297489-A CEPHALOSPORINS BRISTOL-MYERS COMPANY (US) 1981-10-27 US disclosed
JP-S54125628-A PREPARATION OF P-(CHLOROMETHYL) BENZALDEHYDE BANYU PHARMACEUT CO LTD 1979-09-29 JP disclosed
US-4018759-A BACTERICIDES SMITHKLINE CORPORATION (US) 1977-04-19 US disclosed
US-3987041-A P-HYDROXYMETHYLPHENYLACETAMIDOCEPHALOSPORINS SMITHKLINE CORPORATION (US) 1976-10-19 US disclosed
US-3972919-A CHEMICAL INTERMEDIATE FOR ANTIBIOTICS SMITHKLINE CORPORATION (US) 1976-08-03 US disclosed
US-3972919-A CHEMICAL INTERMEDIATE FOR ANTIBIOTICS SMITHKLINE CORPORATION (US) 1976-08-03 US disclosed
US-3962230-A BACTERICIDES SMITHKLINE & FRENCH LABORATORIES, INC. (US) 1976-06-08 US disclosed
US-3957768-A BACTERICIDES SMITHKLINE CORPORATION (US) 1976-05-18 US disclosed
US-3946005-A BACTERICIDES SMITHKLINE CORPORATION (US) 1976-03-23 US disclosed
US-3943129-A BACTERICIDE SMITHKLINE CORPORATION (US) 1976-03-09 US disclosed