SCHEMBL8468381

SCHEMBL8468381

CC(=CC(F)CC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7585571 1.00 THRB (0.34) THRB
SCHEMBL9722510 1.00 THRB (0.34) THRB
SCHEMBL4079444 0.83 THRB (0.32) THRB
SCHEMBL4083937 0.83 THRB (0.32) THRB
SCHEMBL4088653 0.81
SCHEMBL161693 0.80
SCHEMBL534525 0.80
SCHEMBL8512790 0.76 THRB (0.32) THRB
SCHEMBL2420940 0.76 THRB (0.36) THRB
SCHEMBL2415711 0.76 THRB (0.36) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883152-A HARD CONTACT LENS CONSISTING OF A COPOLYMER OF CARBOXYLIC ACID ESTER MONOMER, TRIS(TRIMETHYLSILOXY)SILYLPROPYL(METH)ACRYLATE, AND COPOLYMERIZABLE MONOMER NIPPON OIL AND FATS CO., LTD. (JP) 1999-03-16 US claimed