Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468064 | 0.90 | GAA (0.40) | NPSR1ATMGAAXBP1L3MBTL1 | |
| SCHEMBL8161184 | 0.88 | PPARG (0.44) | NPSR1ATMGAAXBP1L3MBTL1 | |
| SCHEMBL8837906 | 0.87 | AR (0.40) | NPSR1CYP2C19MEN1KMT2AHTT | |
| SCHEMBL8466402 | 0.86 | GAA (0.39) | NPSR1ATMGAAXBP1L3MBTL1 | |
| SCHEMBL8467683 | 0.86 | MAPK1 (0.51) | NPSR1ATMGAAXBP1L3MBTL1 | |
| SCHEMBL8837936 | 0.81 | ALDH1A1 (0.45) | NPSR1ATMGAAL3MBTL1CYP2C19 | |
| SCHEMBL13580950 | 0.78 | ALDH2 (0.38) | NPSR1ATMGAAXBP1L3MBTL1 | |
| SCHEMBL13580954 | 0.78 | ALDH2 (0.38) | NPSR1ATMGAAXBP1L3MBTL1 | |
| SCHEMBL28331362 | 0.77 | SMN1; SMN2 (0.46) | GAACYP2C19MEN1KMT2AHTT | |
| SCHEMBL8468814 | 0.76 | NPSR1 (0.48) | NPSR1ATMGAAXBP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869735-A | Process for the preparation of alkyl aryl ethers containing carboxyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | disclosed |