Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.46 |
| ▸ | AGPAT2 | O15120 | 3/20 | 0.46 |
| ▸ | DHFR | P00374 | 2/20 | 0.45 |
| ▸ | AURKA | O14965 | 4/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1319443 | 0.93 | CA12 (0.53) | CDK9CA12CA1CA2CA9 | |
| SCHEMBL31220992 | 0.85 | CHRNA7 (0.51) | CDK9CA12CA1CA2CA9 | |
| SCHEMBL3734947 | 0.85 | CDK9 (0.56) | CDK9GPR68CHRNA7NPC1RAB9A | |
| SCHEMBL31220973 | 0.83 | CDK9 (0.57) | CDK9GPR68AGPAT2DHFRCHRNA7 | |
| SCHEMBL5959433 | 0.82 | AURKA (0.59) | CA9AURKAKMT2AKDM4EMEN1 | |
| SCHEMBL16697754 | 0.81 | ALDH1A1 (0.54) | CA9AURKAKMT2AKDM4EMEN1 | |
| SCHEMBL31220979 | 0.81 | CHRNA7 (0.47) | CDK9CA12CA1CA2CA9 | |
| SCHEMBL31220974 | 0.81 | CHRNA7 (0.47) | CDK9CA12CA1CA2CA9 | |
| SCHEMBL31220976 | 0.80 | CHRNA7 (0.46) | CDK9CA12CA1CA2CA9 | |
| SCHEMBL10910614 | 0.78 | CA12 (0.68) | CDK9CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869184-A | RESIN RAW MATERIALS FOR PAINTS, ADHESIVES | MITSUI TOATSU CHEMICALS, INC. (JP) | 1999-02-09 | — | — | US | disclosed |
| US-5744504-A | AMINO RESIN; THERMOSETTING MOLDING MATERIALS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-04-28 | — | — | US | disclosed |