Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM3 | Q14832 | 2/20 | 0.66 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.54 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5052894 | 0.81 | CPA3 (0.71) | GRM3FOLH1 | |
| SCHEMBL12145183 | 0.81 | GRM3 (0.68) | GRM3FOLH1 | |
| SCHEMBL5054470 | 0.81 | FOLH1 (0.56) | GRM3FOLH1NAALAD2 | |
| SCHEMBL4135913 | 0.81 | GRM3 (1.00) | GRM3FOLH1NAALAD2 | |
| SCHEMBL1373664 | 0.79 | GRM3 (0.65) | GRM3FOLH1 | |
| SCHEMBL8155082 | 0.79 | FOLH1 (0.59) | GRM3FOLH1NAALAD2 | |
| SCHEMBL1373618 | 0.79 | FOLH1 (0.59) | GRM3FOLH1NAALAD2 | |
| SCHEMBL1373545 | 0.78 | GRM3 (0.54) | GRM3FOLH1 | |
| SCHEMBL1377066 | 0.78 | FOLH1 (0.54) | GRM3FOLH1 | |
| SCHEMBL5053123 | 0.77 | FOLH1 (0.61) | GRM3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999033848-B1 | PROCESS FOR PREPARING ENANTIOMER-ENRICHED HYDROXYPHOSPHINYL DERIVATIVES | GUILFORD PHARM INC (US) | 1999-08-12 | — | — | WO | claimed |