Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466170 | 1.00 | UTS2R (0.50) | UTS2RTSHRTP53ESR1ESR2 | |
| SCHEMBL1785848 | 0.86 | TSHR (0.52) | UTS2RTSHRTP53ESR1ESR2 | |
| SCHEMBL27399397 | 0.83 | UTS2R (0.50) | UTS2RTSHRTP53ESR1ESR2 | |
| SCHEMBL4078629 | 0.83 | ALDH1A1 (0.48) | UTS2RALDH1A1LMNAMAPT | |
| SCHEMBL4087799 | 0.83 | ALDH1A1 (0.48) | UTS2RALDH1A1LMNAMAPT | |
| SCHEMBL570386 | 0.82 | TSHR (0.55) | UTS2RTSHRTP53ESR1ESR2 | |
| SCHEMBL1080913 | 0.82 | TDP1 (0.56) | UTS2RTSHRTP53ESR1ESR2 | |
| SCHEMBL1082047 | 0.82 | TDP1 (0.56) | UTS2RTSHRTP53ESR1ESR2 | |
| SCHEMBL1786364 | 0.82 | TDP1 (0.56) | UTS2RTSHRTP53ESR1ESR2 | |
| SCHEMBL8772074 | 0.81 | PABPC1 (0.51) | UTS2RTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060559-A1 | Process for the preparation of enantiomerically pure 3-hydroxy-3-arylpropylamines and their optical stereoisomers | Cadila Pharmaceuticals Limited (IN) | 2009-05-20 | — | — | EP | disclosed |