SCHEMBL8468752

SCHEMBL8468752

C=C(C)C(=O)OC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CF

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1717867 1.00 ALDH1A1 (0.33) ALDH1A1TSHRTHRB
SCHEMBL9796413 1.00 ALDH1A1 (0.33) ALDH1A1TSHRTHRB
SCHEMBL8165330 1.00 ALDH1A1 (0.33) ALDH1A1TSHRTHRB
SCHEMBL9318470 0.98 ALDH1A1 (0.34) ALDH1A1TSHRTHRB
SCHEMBL320168 0.93 ALDH1A1 (0.35) ALDH1A1TSHRTHRB
SCHEMBL4603430 0.87 ALDH1A1 (0.42) ALDH1A1TSHRTHRB
SCHEMBL5586309 0.86 ALDH1A1 (0.33) ALDH1A1TSHRTHRB
SCHEMBL2784839 0.86 ALDH1A1 (0.33) ALDH1A1TSHRTHRB
SCHEMBL15921862 0.86 ALDH1A1 (0.33) ALDH1A1TSHRTHRB
SCHEMBL8659592 0.86 ALDH1A1 (0.33) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552889-B2 Viscosity index improver, refrigerator oil, and working fluid composition for refrigerators SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2026-02-17 US disclosed
WO-2024210051-A1 VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATOR ENEOS株式会社 2024-10-10 WO disclosed
US-20240309137-A1 VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATORS SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2024-09-19 US disclosed
WO-2024143111-A1 VISCOSITY INDEX IMPROVING AGENT, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATOR ENEOS株式会社 2024-07-04 WO disclosed
EP-4361187-A1 VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATORS Sanyo Chemical Industries, Ltd. (JP) 2024-05-01 EP disclosed
WO-2022270342-A1 VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATORS 三洋化成工業株式会社 2022-12-29 WO disclosed
US-5998531-A NITRILE RUBBER NIPPON ZEON CO LTD (JP) 1999-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552889-B2 Viscosity index improver, refrigerator oil, and working fluid composition for refrigerators F12, BCL2A1, C1R ALDH1A1 2036/4885TSHR 1422/4885THRB 2413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.