Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784839 | 1.00 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR | |
| SCHEMBL15921862 | 1.00 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR | |
| SCHEMBL5586309 | 1.00 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR | |
| SCHEMBL9317622 | 0.93 | ALDH1A1 (0.35) | ALDH1A1THRBTSHR | |
| SCHEMBL4603430 | 0.87 | ALDH1A1 (0.42) | ALDH1A1THRBTSHR | |
| SCHEMBL8851983 | 0.87 | TSHR (0.34) | ALDH1A1THRBTSHR | |
| SCHEMBL9796413 | 0.86 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR | |
| SCHEMBL8165330 | 0.86 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR | |
| SCHEMBL1717867 | 0.86 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR | |
| SCHEMBL9179678 | 0.86 | ALDH1A1 (0.33) | ALDH1A1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9415123-B2 | Polymeric nanoparticles for ultrasound imaging and therapy | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-08-16 | — | — | US | disclosed |
| US-20140243664-A1 | Polymeric Nanoparticles for Ultrasound Imaging and Therapy | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2014-08-28 | — | — | US | disclosed |
| WO-2013055791-A1 | POLYMERIC NANOPARTICLES FOR ULTRASOUND IMAGING AND THERAPY | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-04-18 | — | — | WO | disclosed |
| EP-0862737-A1 | CHROMOTOGRAPHIC METHOD AND DEVICE IN WHICH A CONTINUOUS MACROPOROUS ORGANIC MATRIX IS USED | Pharmacia Biotech AB (SE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997019347-A1 | CHROMOTOGRAPHIC METHOD AND DEVICE IN WHICH A CONTINUOUS MACROPOROUS ORGANIC MATRIX IS USED | PHARMACIA BIOTECH AB (SE) | 1997-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140243664-A1 | Polymeric Nanoparticles for Ultrasound Imaging and Therapy | FGB, MMAB, VHL | ALDH1A1 2631/4885THRB 896/4885TSHR 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.