SCHEMBL8468757

SCHEMBL8468757

C=C(C)C(=O)OC(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.35
TSHR P16473 3/20 0.34
KDM4E B2RXH2 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.33
USP2 O75604 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4108175 1.00 GAA (0.35) GAATSHRKDM4ETDP1ALDH1A1
SCHEMBL1717872 1.00 GAA (0.35) GAATSHRKDM4ETDP1ALDH1A1
SCHEMBL8165333 1.00 GAA (0.35) GAATSHRKDM4ETDP1ALDH1A1
SCHEMBL28724941 0.98 GAA (0.35) GAATSHRKDM4ETDP1ALDH1A1
SCHEMBL4108841 0.95 TSHR (0.39) GAATSHRKDM4ETDP1ALDH1A1
SCHEMBL1444292 0.90 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL8447490 0.90 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL15157588 0.90 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL1444151 0.90 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL15156807 0.90 ALDH1A1 (0.33) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552889-B2 Viscosity index improver, refrigerator oil, and working fluid composition for refrigerators SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2026-02-17 US disclosed
WO-2024210051-A1 VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATOR ENEOS株式会社 2024-10-10 WO disclosed
US-20240309137-A1 VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATORS SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2024-09-19 US disclosed
WO-2024143111-A1 VISCOSITY INDEX IMPROVING AGENT, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATOR ENEOS株式会社 2024-07-04 WO disclosed
EP-4361187-A1 VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATORS Sanyo Chemical Industries, Ltd. (JP) 2024-05-01 EP disclosed
WO-2022270342-A1 VISCOSITY INDEX IMPROVER, REFRIGERATOR OIL, AND WORKING FLUID COMPOSITION FOR REFRIGERATORS 三洋化成工業株式会社 2022-12-29 WO disclosed
US-5998531-A NITRILE RUBBER NIPPON ZEON CO LTD (JP) 1999-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552889-B2 Viscosity index improver, refrigerator oil, and working fluid composition for refrigerators F12, BCL2A1, C1R GAA 4606/4885TSHR 1422/4885KDM4E 3781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.