Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8468285 | 0.75 | MAOB (0.37) | HTR2CHTR2AHTR2BADRA1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL8468856 | 0.75 | KDM1A (0.45) | HTR2CSLC6A2SLC6A4MAPT | |
| SCHEMBL12875534 | 0.70 | HTR2C (0.59) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8468874 | 0.70 | HTR2A (0.36) | HTR2CHTR2AHTR2BSLC6A2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL267935 | 0.69 | HTR2C (0.57) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8467888 | 0.67 | KDM1A (0.41) | HTR2CHTR2B | |
| SCHEMBL31113521 | 0.66 | KDM1A (0.62) | HTR2CHTR2AHTR2BADRA1A | |
| SCHEMBL7864304 | 0.66 | KDM1A (0.62) | HTR2CHTR2AHTR2BADRA1A | |
| SCHEMBL16591167 | 0.66 | HTR2C (0.57) | HTR2CHTR2AHTR2BMEN1KMT2A | |
| SCHEMBL7092178 | 0.66 | KDM1A (0.62) | HTR2CHTR2AHTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819705-B1 | Olefin polymerization | PHILLIPS PETROLEUM CO (US) | 1999-09-08 | — | — | EP | disclosed |