Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469259 | 0.93 | REN (0.36) | THRBRENALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL8469312 | 0.93 | REN (0.36) | THRBRENALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL8468849 | 0.90 | REN (0.36) | THRBRENALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL4582508 | 0.89 | REN (0.36) | THRBRENALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL4582503 | 0.89 | REN (0.36) | THRBRENALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL8469161 | 0.85 | THRB (0.34) | THRBRENALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL4582528 | 0.84 | REN (0.33) | RENRORC | |
| SCHEMBL4582521 | 0.84 | REN (0.33) | RENRORC | |
| SCHEMBL4582524 | 0.84 | REN (0.33) | RENRORC | |
| SCHEMBL4582658 | 0.83 | HRH2 (0.35) | RENCACNA1BHRH2HRH1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908762-A2 | Organic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |