Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 15/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5787307 | 0.79 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5787887 | 0.66 | CRHR1 (0.45) | CRHR1 | |
| SCHEMBL5789704 | 0.66 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5889600 | 0.64 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL5945279 | 0.64 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL5789329 | 0.63 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL2584391 | 0.62 | CRHR1 (0.42) | CRHR1 | |
| SCHEMBL5789966 | 0.62 | CRHR1 (0.43) | CRHR1 | |
| SCHEMBL5465128 | 0.62 | CRHR1 (0.52) | CRHR1 | |
| SCHEMBL5788784 | 0.61 | CRHR1 (0.43) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923582-A1 | SUBSTITUTED 6,5-HETERO-BICYCLIC DERIVATIVES | PFIZER INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008847-A1 | SUBSTITUTED 6,5-HETERO-BICYCLIC DERIVATIVES | PFIZER INC. (US) | 1998-03-05 | — | — | WO | disclosed |