SCHEMBL8469151

SCHEMBL8469151

C=C(C)C(=O)CC(C)C(C)=O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4077076 0.79
SCHEMBL13235783 0.79
SCHEMBL15295735 0.79
SCHEMBL11413301 0.78 ALDH1A1 (0.35) TSHRTDP1ALDH1A1
SCHEMBL481170 0.77
SCHEMBL20029568 0.77
SCHEMBL23248545 0.75
SCHEMBL20804159 0.75
SCHEMBL880629 0.75 TSHR (0.37) TSHRTDP1ALDH1A1CA2
SCHEMBL8595701 0.74 SLC22A6 (0.41) TSHRTDP1ALDH1A1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5900462-A DEHYDRATION REACTION OF A KETONE AND ALCOHOL; HIGH DENSITY CROSSLINKING TOYO INK MANUFACTURING CO., LTD. (JP) 1999-05-04 US disclosed