⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL481170 | 0.81 | — | — | |
| SCHEMBL8469151 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL23248545 | 0.79 | — | — | |
| SCHEMBL880629 | 0.79 | TSHR (0.37) | — | |
| SCHEMBL16424258 | 0.79 | ALDH1A1 (0.48) | — | |
| SCHEMBL108864 | 0.78 | CA2 (0.61) | — | |
| SCHEMBL8595701 | 0.78 | SLC22A6 (0.41) | — | |
| SCHEMBL25404425 | 0.77 | — | — | |
| SCHEMBL93309 | 0.77 | — | — | |
| SCHEMBL8817533 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230324801-A1 | UNDERLAYER FILM FORMING COMPOSITION FOR LITHOGRAPHY, UNDERLAYER FILM, AND PATTERN FORMATION METHOD | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2023-10-12 | — | — | US | disclosed |
| US-11110175-B2 | Compositions with permeation enhancers for drug delivery | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2021-09-07 | — | — | US | disclosed |
| CN-105801394-B | The method that methacrolein is prepared by the tert-butyl alcohol | 上海华谊新材料有限公司 | 2018-10-02 | — | — | CN | disclosed |
| US-20180153894-A1 | FUSED BICYCLIC PYRIMIDINE DERIVATIVES AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-06-07 | — | — | US | disclosed |
| US-9980964-B2 | ERK inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2018-05-29 | — | — | US | disclosed |
| US-20180022713-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2018-01-25 | — | — | US | disclosed |
| US-9796700-B2 | ERK inhibitors and uses thereof | CELGENE CAR LLC (BM) | 2017-10-24 | — | — | US | disclosed |
| US-20170267685-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2017-09-21 | — | — | US | disclosed |
| US-20170210729-A1 | ERK INHIBITORS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2017-07-27 | — | — | US | disclosed |
| US-9695132-B2 | Heteroaryl compounds and uses thereof | CELGENE CAR LLC (BM) | 2017-07-04 | — | — | US | disclosed |
| US-20160046634-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2016-02-18 | — | — | US | disclosed |
| US-20160002176-A1 | ERK INHIBITORS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2016-01-07 | — | — | US | disclosed |
| US-9145387-B2 | ERK inhibitors and uses thereof | CELGENE AVILOMICS RESEARCH, INC. (US) | 2015-09-29 | — | — | US | disclosed |
| US-20140296233-A1 | HETEROARYL COMPOUNDS AND USES THEREOF | SANOFI (FR) | 2014-10-02 | — | — | US | disclosed |
| US-20140235782-A1 | MACROMONOMER MIXTURE, TERMINAL-REACTIVE POLYMER MIXTURE, INTERMEDIATE FOR MACROMONOMER AND SILICONE HYDROGEL | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140228322-A1 | ERK INHIBITORS AND USES THEREOF | CELGENE AVILOMICS RESEARCH, INC. (US) | 2014-08-14 | — | — | US | disclosed |
| US-8748548-B2 | Macromonomer mixture, terminal-reactive polymer mixture, intermediate for macromonomer and silicone hydrogel | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-06-10 | — | — | US | disclosed |
| US-20110160385-A1 | MACROMONOMER MIXTURE, TERMINAL-REACTIVE POLYMER MIXTURE, INTERMEDIATE FOR MACROMONOMER AND SILICONE HYDROGEL | JOHNSON & JOHNSON VISION CARE, INC. | 2011-06-30 | — | — | US | disclosed |
| JP-2009114414-A | WATER ABSORBING RESIN PARTICLE, ABSORBER AND ABSORPTIVE ARTICLE | SAN-DIA POLYMER LTD | 2009-05-28 | — | — | JP | disclosed |
| US-20080187516-A1 | ACYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |