Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18239536 | 1.00 | TSHR (0.53) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL154640 | 0.95 | NAAA (0.48) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL1871015 | 0.95 | NAAA (0.48) | TSHRHPGDATMALDH1A1HCAR2 | |
| Decanal SCHEMBL5170816 | 0.85 | TSHR (0.46) | TSHRHPGDHCAR2NAAADGKA | |
| SCHEMBL5689545 | 0.83 | TSHR (0.55) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL2878558 | 0.80 | ALDH1A1 (0.39) | TSHRALDH1A1HCAR2L3MBTL1NPSR1 | |
| SCHEMBL27367021 | 0.80 | ATM (0.46) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL27367011 | 0.80 | ATM (0.46) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL15218038 | 0.79 | TSHR (0.50) | TSHRHPGDATMALDH1A1HCAR2 | |
| SCHEMBL3688622 | 0.78 | TSHR (0.53) | TSHRHPGDATMALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610730-B2 | Viricides; protease inbhibitor | AGOURON PHARMACEUTICALS, INC. | 2003-08-26 | — | — | US | disclosed |