SCHEMBL8469266

SCHEMBL8469266

O=C(Nc1ccccc1)c1cccc(Cl)c1OCl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMO Q99835 4/20 0.56
KCNK3 O14649 1/20 0.56
KCNK9 Q9NPC2 1/20 0.56
ALDH1A1 P00352 1/20 0.53
JAK2 O60674 2/20 0.53
TYK2 P29597 1/20 0.53
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
NPC1 O15118 1/20 0.52
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HPGD P15428 2/20 0.51
KDM4E B2RXH2 1/20 0.51
LMNA P02545 1/20 0.51
TP53 P04637 1/20 0.51
HTT P42858 1/20 0.51
HSD17B10 Q99714 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28017780 0.98 SMO (0.55) SMOKCNK3KCNK9ALDH1A1JAK2
SCHEMBL28913528 0.86 SMO (0.55) SMOKCNK3KCNK9ALDH1A1JAK2
SCHEMBL8988366 0.86 SMO (0.55) SMOKCNK3KCNK9ALDH1A1JAK2
SCHEMBL28388092 0.84 MEN1 (0.65) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL29158013 0.84 KMT2A (0.53) SMOALDH1A1JAK2TYK2MEN1
SCHEMBL1648370 0.83 GPR27 (0.53) SMOKCNK3KCNK9ALDH1A1JAK2
SCHEMBL791285 0.83 KMT2A (0.61) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL8741299 0.82 MAPT (0.56) ALDH1A1MEN1KMT2ANPC1MAPT
Ammonia Solution, Strong SCHEMBL29276588 0.82 KMT2A (0.60) ALDH1A1MEN1KMT2ATDP1NPC1
SCHEMBL1203522 0.81 SMO (0.80) SMOKCNK3KCNK9ALDH1A1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105806927-B The ion mobility spectrometry rapid detection method of 3 kinds of bromos or Chlorosalicylic anilide in cosmetics 中国检验检疫科学研究院 2018-08-17 CN claimed
CN-105806927-A Quick detection method for ionic migration spectrum of 3 types of bromo or chloro salicyloyl anilines in cosmetics 中国检验检疫科学研究院 2016-07-27 CN claimed
CN-102600761-A Surface active substance taking N-(4-nitrobenzophenone)-5-chlorosamide as parent, and preparation technology GANNAN NORMAL COLLEGE 2012-07-25 CN claimed
CN-105806927-B The ion mobility spectrometry rapid detection method of 3 kinds of bromos or Chlorosalicylic anilide in cosmetics 中国检验检疫科学研究院 2018-08-17 CN disclosed
CN-102600761-B Surface active substance taking N-(4-nitrobenzophenone)-5-chlorosamide as parent, and preparation technology 赣南师范学院 2017-02-08 CN disclosed
CN-105806927-A Quick detection method for ionic migration spectrum of 3 types of bromo or chloro salicyloyl anilines in cosmetics 中国检验检疫科学研究院 2016-07-27 CN disclosed
CN-103004763-A Ultra-low-capacity niclosamide spray for killing oncomelania and preparation method of spray JIANGSU INST PARASITIC DISEASES 2013-04-03 CN disclosed
CN-102861014-A Worm-disease-resisting compound niclosamide tablet for beasts and birds and preparation method thereof TIANJIN BIJIA PHARM GROUP CO 2013-01-09 CN disclosed
CN-102600761-A Surface active substance taking N-(4-nitrobenzophenone)-5-chlorosamide as parent, and preparation technology GANNAN NORMAL COLLEGE 2012-07-25 CN disclosed
WO-1999035911-A1 ANTIMICROBIAL TOOTHBRUSH UNILEVER PLC (GB) 1999-07-22 WO disclosed