SCHEMBL1648370

SCHEMBL1648370

O=C(Nc1ccccc1)c1ccc(Cl)c(Cl)c1OCl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR27 Q9NS67 1/20 0.53
MEN1 O00255 7/20 0.48
KMT2A Q03164 7/20 0.48
MAPT P10636 4/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C9 P11712 3/20 0.48
LMNA P02545 3/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2C19 P33261 2/20 0.48
TP53 P04637 2/20 0.48
PPARG P37231 2/20 0.48
MAPK1 P28482 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
PKM P14618 1/20 0.48
TSHR P16473 1/20 0.48
NFKB1 P19838 1/20 0.48
THPO P40225 1/20 0.48
MTOR P42345 1/20 0.48
RORC P51449 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8469626 0.84 CHRNB2 (0.48) GPR27MEN1KMT2AMAPTCYP1A2
SCHEMBL649648 0.84 PPARG (0.49) GPR27MEN1KMT2AMAPTCYP1A2
SCHEMBL8469266 0.83 SMO (0.56) MEN1KMT2AMAPTCYP2C9LMNA
Potassium SCHEMBL15568160 0.82 PPARG (0.48) GPR27MEN1KMT2AMAPTCYP1A2
SCHEMBL15568158 0.82 PPARG (0.48) GPR27MEN1KMT2AMAPTCYP1A2
SCHEMBL28017780 0.82 SMO (0.55) MEN1KMT2AMAPTCYP2C9LMNA
SCHEMBL8460416 0.81 AURKA (0.47) GPR27MEN1KMT2AMAPTCYP1A2
SCHEMBL8458244 0.81 MEN1 (0.52) MEN1KMT2AMAPTCYP1A2CYP2C9
SCHEMBL28091035 0.80 GPR27 (0.57) GPR27MEN1KMT2AMAPTCYP1A2
Salicylanilide SCHEMBL27837552 0.77 MEN1 (0.60) MEN1KMT2ALMNATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115916147-A Anti-acne composition 欧莱雅 2023-04-04 CN claimed
EP-2229135-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS L'Oréal (FR) 2010-09-22 EP claimed
WO-2009077453-A1 SOLID ANTIPERSPIRANT AND/OR DEODORANT COMPOSITION IN THE FORM OF A WATER-IN-OIL EMULSION BASED ON SILICONE EMULSIFIERS AND ON WAXES; METHOD FOR TREATING BODY ODOURS L'OREAL (FR) 2009-06-25 WO claimed
JP-64000012-A None JP disclosed
CN-119365547-A Particles for forming pickering emulsions and the like 麒麟控股株式会社 2025-01-24 CN disclosed
EP-4003276-A1 ANHYDROUS ANTIPERSPIRANT AND DEODORANT COMPOSITION, PROCESS FOR ITS PRODUCTION AND USE THEREOF L'OREAL (FR) 2022-06-01 EP disclosed
EP-3897512-A1 WASHABLE DISPERSION OF POLYMER PARTICLES DISPERSED IN A NONAQUEOUS MEDIUM L'OREAL (FR) 2021-10-27 EP disclosed
CN-107530237-B Calcium-based dentifrice for enhancing the absorption rate of active ingredients 高露洁-棕榄公司 2021-04-23 CN disclosed
WO-2021016683-A1 ANHYDROUS ANTIPERSPIRANT AND DEODORANT COMPOSITION, PROCESS FOR ITS PRODUCTION AND USE THEREOF L'OREAL (FR) 2021-02-04 WO disclosed
US-20210016290-A1 PIPETTE TIP RACK BIOTIX, INC. 2021-01-21 US disclosed
WO-2020127733-A1 WASHABLE DISPERSION OF POLYMER PARTICLES DISPERSED IN A NONAQUEOUS MEDIUM L'OREAL (FR) 2020-06-25 WO disclosed
EP-0279328-B1 PERFUMING COMPOSITION WITH A DEODORIZING OR ANTIPERSPIRANT ACTIVITY FIRMENICH SA (CH) 1992-06-03 EP disclosed
WO-1992007587-A1 METHODS AND COMPOSITIONS FOR AMELIORATION OF SKIN WRINKLES NARHEX LIMITED (HK) 1992-05-14 WO disclosed
WO-1992000722-A1 ALCOHOLIC FRAGRANCE COMPOSITION FIRMENICH S.A. (CH) 1992-01-23 WO disclosed
US-4990381-A Coextrusion FIRMENICH S.A. (CH) 1991-02-05 US disclosed
EP-0384034-A2 Perfuming composition with a deodorant or antiperspirant activity FIRMENICH SA (CH) 1990-08-29 EP disclosed
US-4803195-A FILM FORMING SUBSTRATE AND EMULSIFIER; RELEASE IN RESPONSE TO SWEATING FIRMENICH S.A. (CH) 1989-02-07 US disclosed
EP-0300286-A2 Multilayer sandwich sheet and its use in packaging FIRMENICH SA (CH) 1989-01-25 EP disclosed
JP-S6412-A AROMA-IMPARTING COMPOSITION HAVING DEODORANT OR PERSPIRATION-SUPPRESSING ACTION AND DEODORANT OR PERSPIRATION-SUPPRESSING PRODUCT FIRMENICH SA 1989-01-05 JP disclosed
EP-0279328-A2 Perfuming composition with a deodorizing or antiperspirant activity FIRMENICH SA (CH) 1988-08-24 EP disclosed