SCHEMBL8469335

SCHEMBL8469335

O=C=NC1(N=C=O)C=CC(C(=O)c2ccccc2)C=C1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.35
MAPT P10636 2/20 0.35
ALOX15 P16050 1/20 0.35
HBB P68871 1/20 0.35
EPHX1 P07099 2/20 0.34
HSD17B10 Q99714 3/20 0.33
POLB P06746 2/20 0.33
GAA P10253 1/20 0.33
CES1 P23141 3/20 0.32
CES2 O00748 2/20 0.32
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32
DAO P14920 1/20 0.32
NAPRT Q6XQN6 1/20 0.32
MCL1 Q07820 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CYP1A2 P05177 2/20 0.31
CYP2C19 P33261 2/20 0.31
MEN1 O00255 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2768966 0.86 HTT (0.34) HTTMAPTALOX15HBBEPHX1
SCHEMBL1404328 0.77 TOP2A (0.42) MAPTEPHX1HSD17B10POLBGAA
SCHEMBL136598 0.75 MAPT (0.41) HTTMAPTALOX15HBBEPHX1
SCHEMBL659656 0.74 GSK3B (0.41) HTTMAPTALOX15HBBEPHX1
SCHEMBL156512 0.74 MAPT (0.40) HTTMAPTALOX15HBBEPHX1
SCHEMBL363122 0.74 MAPT (0.40) HTTMAPTALOX15HBBEPHX1
SCHEMBL3270605 0.74 MAPT (0.40) HTTMAPTALOX15HBBEPHX1
SCHEMBL528381 0.74 MAPT (0.40) HTTMAPTALOX15HBBEPHX1
SCHEMBL993045 0.74 CES1 (0.45) HTTMAPTALOX15HBBEPHX1
SCHEMBL2470208 0.74 EPHX1 (0.43) HTTMAPTALOX15HBBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137780-B Preparation of polyamideimides 亨斯迈先进材料许可(瑞士)有限公司 2021-07-30 CN claimed
CN-117500895-A Adhesive composition, adhesive sheet, electromagnetic wave shielding material, laminate, and printed wiring board 东洋纺MC株式会社 2024-02-02 CN disclosed
CN-117280429-A Insulated wire 住友电气工业株式会社 2023-12-22 CN disclosed
CN-116918007-A insulated wire 住友电气工业株式会社 2023-10-20 CN disclosed
CN-116887981-A Laminated film, method for producing laminated film, laminated body, and method for producing laminated body 东洋纺株式会社 2023-10-13 CN disclosed
CN-113286835-B Adhesive composition containing dimeric alcohol copolymerized polyimide polyurethane resin 东洋纺MC株式会社 2023-09-29 CN disclosed
CN-116829655-A Electrodeposition liquid and method for producing insulating film 三菱综合材料株式会社 2023-09-29 CN disclosed
CN-116724089-A Insulated wire 住友电气工业株式会社 2023-09-08 CN disclosed
CN-116635481-A Insulated wire and method for manufacturing the same 住友电气工业株式会社 2023-08-22 CN disclosed
CN-115398565-A Insulated wire and method for manufacturing same 住友电气工业株式会社 2022-11-25 CN disclosed
CN-108290996-B High performance polyurethane prepolymers and cured compositions 朗盛解决方案美国公司 2021-03-30 CN disclosed
CN-108368412-B Adhesive composition using polyamideimide resin 东洋纺株式会社 2020-12-22 CN disclosed
CN-107849210-B Urethane-modified polyimide resin solution 东洋纺株式会社 2020-09-11 CN disclosed
CN-108431905-B Insulated wire 住友电气工业株式会社 2020-05-05 CN disclosed
CN-110574128-A Insulated wire 住友电气工业株式会社 2019-12-13 CN disclosed
CN-1211698-C Liquid crystal directional membrane and liquid crystal displaying componnet JSR CORP (JP) 2005-07-20 CN disclosed
CN-1306222-A Liquid crystal directional membrane and liquid crystal displaying componnet JSR CORP (JP) 2001-08-01 CN disclosed
EP-0897401-A1 POLYURETHANE COMPOSITION USEFUL FOR COATING CYLINDRICAL PARTS UNIROYAL CHEMICAL COMPANY, Inc. (US) 1999-02-24 EP disclosed
WO-1997042246-A1 POLYURETHANE COMPOSITION USEFUL FOR COATING CYLINDRICAL PARTS UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-11-13 WO disclosed
EP-0635034-A1 POLYURETHANE ELASTOMER AND NON-PNEUMATIC TIRE FABRICATED THEREFROM. UNIROYAL CHEM CO INC (US) 1995-01-25 EP disclosed