SCHEMBL846938

SCHEMBL846938

CC(CO)(CO)C(=O)OCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.56
KMT2A Q03164 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
LMNA P02545 2/20 0.46
HCAR2 Q8TDS4 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44
PRKCA P17252 1/20 0.44
PRKCD Q05655 1/20 0.44
MAOB P27338 1/20 0.44
PTPRC P08575 1/20 0.43
PTPN1 P18031 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27161900 0.94 ALDH1A1 (0.50) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL12565582 0.92 ALDH1A1 (0.51) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL16370059 0.90 ALDH1A1 (0.50) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL20465366 0.88 ALDH1A1 (0.47) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL15581005 0.88 ALDH1A1 (0.60) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL621696 0.86 ALDH1A1 (0.56) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL11015123 0.86 ALDH1A1 (0.56) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL2032918 0.84 ALDH1A1 (0.55) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL16699608 0.84 ALDH1A1 (0.55) ALDH1A1KMT2ATDP1MAPK1L3MBTL1
SCHEMBL17430945 0.84 MAOB (0.45) ALDH1A1NPC1RAB9AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 327 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117417515-B 2-methyl-2-carbobenzoxy-1, 3-propanediol modified PBAT material and preparation method thereof 康辉新材料科技有限公司 2024-04-12 CN claimed
CN-117417515-A 2-methyl-2-carbobenzoxy-1, 3-propanediol modified PBAT material and preparation method thereof 康辉新材料科技有限公司 2024-01-19 CN claimed
CN-109054010-B Imidazole ring modified acid-sensitive polycarbonate material and preparation and application thereof 沈阳信达泰康医药科技有限公司 2022-08-16 CN claimed
EP-4747258-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Tenvie Therapeutics, Inc. (US) 2026-05-27 EP disclosed
EP-4531923-A1 SMALL MOLECULE CONJUGATED CHARGE-ALTERING RELEASABLE TRANSPORTERS FOR NUCLEIC ACID DELIVERY The Board of Trustees of the Leland Stanford Junior University (US) 2025-04-09 EP disclosed
WO-2025024329-A2 COMPOUNDS, COMPOSITIONS, AND METHODS NICO THERAPEUTICS, INC. (US) 2025-01-30 WO disclosed
US-20240252677-A1 ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2024-08-01 US disclosed
US-12006337-B2 Mitogen-activated protein kinase inhibitors, methods of making, and methods of use thereof WASHINGTON UNIVERSITY (US) 2024-06-11 US disclosed
CN-117417515-B 2-methyl-2-carbobenzoxy-1, 3-propanediol modified PBAT material and preparation method thereof 康辉新材料科技有限公司 2024-04-12 CN disclosed
CN-117417515-B 2-methyl-2-carbobenzoxy-1, 3-propanediol modified PBAT material and preparation method thereof 康辉新材料科技有限公司 2024-04-12 CN disclosed
CN-117417515-B 2-methyl-2-carbobenzoxy-1, 3-propanediol modified PBAT material and preparation method thereof 康辉新材料科技有限公司 2024-04-12 CN disclosed
US-6458772-B1 Prodrugs MEDIVIR AB (SE) 2002-10-01 US disclosed
US-6399666-B1 FOR MICROCIRCUIT; DECOMPOSABLE POLYMER AND DIELECTRIC INTERNATIONAL BUSINESS MACHINES CORPORATION 2002-06-04 US disclosed
EP-1123935-A2 3'-Fluorinated guanosine derivatives for the treatment or prophylaxis of HBV or retroviral infections MEDIVIR AB (SE) 2001-08-16 EP disclosed
EP-0988304-B1 NUCLEOSIDES ANALOGUES, SUCH AS ANTIVIRALS INCLUDING INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTASE AND THE DNA POLYMERASE OF HEPATITIS B VIRUS (HBV) MEDIVIR AB (SE) 2001-05-02 EP disclosed
EP-0988304-A1 NUCLEOSIDES ANALOGUES, SUCH AS ANTIVIRALS INCLUDING INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTASE AND THE DNA POLYMERASE OF HEPATITIS B VIRUS (HBV) MEDIVIR AB (SE) 2000-03-29 EP disclosed
EP-0942916-A2 NUCLEOSIDES Medivir Aktiebolag (SE) 1999-09-22 EP disclosed
WO-1999009031-A1 NUCLEOSIDES ANALOGUES, SUCH AS ANTIVIRALS INCLUDING INHIBITORS OF RETROVIRAL REVERSE TRANSCRIPTASE AND THE DNA POLYMERASE OF HEPATITIS B VIRUS (HBV) MEDIVIR AB (SE) 1999-02-25 WO disclosed
WO-1999000440-A1 SYNTHESIS OF A DENDRITIC POLYALCOHOL PERSTORP AB (SE) 1999-01-07 WO disclosed
WO-1998021223-A1 NUCLEOSIDES MEDIVIR AB (SE) 1998-05-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12006337-B2 Mitogen-activated protein kinase inhibitors, methods of making, and methods of use thereof MAPK13, MAPK12, MAP3K13 ALDH1A1 3887/4885KMT2A 3281/4885TDP1 2011/4885
US-20240252677-A1 ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS TLR3, TLR9, ADAR ALDH1A1 2968/4885KMT2A 1037/4885TDP1 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.