SCHEMBL8469476

SCHEMBL8469476

COc1ccc(C2CC3=CC=CCC3C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
ALDH1A1 P00352 4/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ADRA1A P35348 1/20 0.37
DRD2 P14416 1/20 0.36
HTR2C P28335 1/20 0.36
ALOX15 P16050 2/20 0.35
ALOX12 P18054 2/20 0.35
MAPT P10636 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27416243 0.83 MAP1LC3B (0.33) HTR2CALOX15ALOX12
SCHEMBL8469131 0.80 KDM1A (0.35) KDM1AMAOBHTR2C
SCHEMBL8469379 0.79 GAA (0.36) KDM1AMAOAMAOBADRA1AHTR2C
SCHEMBL11714356 0.74 KDM1A (0.59) KDM1AMAOAMAOBALDH1A1KMT2A
SCHEMBL12227833 0.74 KDM1A (0.59) KDM1AMAOAMAOBALDH1A1KMT2A
SCHEMBL10318008 0.70
SCHEMBL2360998 0.70
SCHEMBL12227834 0.69 KDM1A (0.53) KDM1AMAOAMAOBALDH1A1KMT2A
Hydrochloric Acid SCHEMBL8468857 0.69 KDM1A (0.43) KDM1AMAOAMAOBADRA1ADRD2
SCHEMBL30951776 0.68 KDM1A (0.52) KDM1AMAOAMAOBALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1113070-C Olefines polymerizing PHILLIPS PETROLEUM CO (US) 2003-07-02 CN disclosed
EP-0819705-B1 Olefin polymerization PHILLIPS PETROLEUM CO (US) 1999-09-08 EP disclosed
CN-1182749-A Olefines polymerizing PHILLIPS PETROLEUM CO (US) 1998-05-27 CN disclosed
EP-0819705-A1 Olefin polymerization PHILLIPS PETROLEUM COMPANY (US) 1998-01-21 EP disclosed