SCHEMBL8469131

SCHEMBL8469131

Brc1ccc(C2CC3=CC=CCC3C2)cc1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.35
KCNH2 Q12809 2/20 0.35
MAOB P27338 2/20 0.35
RCOR1 Q9UKL0 2/20 0.35
KDM1B Q8NB78 1/20 0.35
BRD4 O60885 1/20 0.35
HTR2C P28335 2/20 0.32
HTR2B P41595 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27416243 0.83 MAP1LC3B (0.33) HTR2CHTR2B
SCHEMBL8469379 0.83 GAA (0.36) KDM1AKCNH2MAOBRCOR1BRD4
SCHEMBL8469476 0.80 KDM1A (0.40) KDM1AMAOBHTR2C
SCHEMBL2360998 0.73
SCHEMBL5889192 0.67
SCHEMBL12656250 0.67
SCHEMBL27498802 0.67
SCHEMBL7856504 0.66
Hydrochloric Acid SCHEMBL8467891 0.65 KDM1A (0.38) KDM1AKCNH2MAOBRCOR1KDM1B
SCHEMBL28305162 0.65 BRD4 (0.46) KDM1AKCNH2MAOBRCOR1KDM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0819705-B1 Olefin polymerization PHILLIPS PETROLEUM CO (US) 1999-09-08 EP disclosed
EP-0819705-A1 Olefin polymerization PHILLIPS PETROLEUM COMPANY (US) 1998-01-21 EP disclosed
US-5705579-A CATALYTIC OLEFIN POLYMERIZATION WITH BIS/2-P-METHOXYPHENYL/ TETRAHYDROINDENYL/ ZIRCONIUM DICHLORIDE AND ALKYLALUMINOXANE PHILLIPS PETROLEUM COMPANY (US) 1998-01-06 US disclosed