Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469581 | 0.87 | ALDH1A1 (0.37) | DHODHALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL229607 | 0.75 | KMT2A (0.44) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL1253211 | 0.75 | MAPT (0.34) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10841299 | 0.74 | KMT2A (0.43) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL8977401 | 0.74 | OPRL1 (0.39) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8059849 | 0.74 | KDM4E (0.54) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL14022216 | 0.73 | — | — | |
| SCHEMBL8073985 | 0.73 | TERT (0.54) | ALDH1A1MAPTMEN1KMT2AALOX15 | |
| SCHEMBL8059909 | 0.73 | TERT (0.54) | ALDH1A1MAPTMEN1KMT2AALOX15 | |
| Methyl Alcohol SCHEMBL4797570 | 0.73 | CYP1A2 (0.46) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1048245-C | Novel 5-pyrrolyl-2-pyridylmethylsulfinyl benzimidazole derivatives | IL YANG PHARM CO LTD (KR) | 2000-01-12 | — | — | CN | disclosed |
| EP-0696281-B1 | NOVEL 5-PYRROLYL-2-PYRIDYLMETHYLSULFINYL BENZIMIDAZOLE DERIVATIVES | IL YANG PHARM CO LTD (KR) | 1999-05-12 | — | — | EP | disclosed |
| US-5703097-A | ANTIULCER AGENTS | IL-YANG PHARM. CO., LTD. (KR) | 1997-12-30 | — | — | US | disclosed |
| CN-1121714-A | Novel 5-pyrrolyl-2-pyridylmethylsulfinyl benzimidazole derivatives | IL YANG PHARM CO LTD (KR) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696281-A1 | NOVEL 5-PYRROLYL-2-PYRIDYLMETHYLSULFINYL BENZIMIDAZOLE DERIVATIVES | IL-YANG PHARM. CO., LTD. (KR) | 1996-02-14 | — | — | EP | disclosed |
| WO-1995023140-A1 | NOVEL 5-PYRROLYL-2-PYRIDYLMETHYLSULFINYL BENZIMIDAZOLE DERIVATIVES | IL-YANG PHARM. CO., LTD. (KR) | 1995-08-31 | — | — | WO | disclosed |