Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | CDC25B | P30305 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PTPRC | P08575 | 2/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthoquinone SCHEMBL8523737 | 0.83 | TSHR (0.62) | TSHRCDC25BMAPK1ALDH1A1PTPRC | |
| SCHEMBL27380 | 0.83 | TSHR (1.00) | TSHRLMNAALDH1A1CA1CA2 | |
| Benzene SCHEMBL27997624 | 0.83 | TSHR (1.00) | TSHRLMNAALDH1A1CA1CA2 | |
| SCHEMBL5311581 | 0.83 | TSHR (1.00) | TSHRLMNAALDH1A1CA1CA2 | |
| SCHEMBL28301231 | 0.80 | TSHR (0.83) | TSHRKMT2AMAPK1MAPTSMN1; SMN2 | |
| SCHEMBL1009266 | 0.80 | TSHR (0.94) | TSHRLMNAALDH1A1CA1CA2 | |
| SCHEMBL9491202 | 0.80 | TSHR (0.94) | TSHRLMNAALDH1A1CA1CA2 | |
| Methane SCHEMBL11192510 | 0.80 | TSHR (0.94) | TSHRLMNAALDH1A1CA1CA2 | |
| SCHEMBL10317949 | 0.80 | TSHR (0.94) | TSHRLMNAALDH1A1CA1CA2 | |
| SCHEMBL9725547 | 0.80 | TSHR (0.94) | TSHRLMNAALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5942370-A | MULTICOLOR PHOTOPOLYMERIZATION | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-08-24 | — | — | US | disclosed |
| US-5677107-A | PHOTOHARDENABLE FILM WITH PHOTORESPONSIVE AGENT; IRRADIATING SELECTIVE PORTIONS OF CROSS-SECTIONAL PATTERNS THAT ARE TO BE COLORED DIFFERENTLY | SPECTRA GROUP LIMITED, INC. (US) | 1997-10-14 | — | — | US | disclosed |