Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14829176 | 0.81 | NAPRT (0.41) | NAPRTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6865182 | 0.81 | NAPRT (0.55) | NAPRTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2113397 | 0.81 | NAPRT (0.41) | NAPRTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7431725 | 0.78 | PDPK1 (0.42) | PDPK1NAPRTALDH1A1HPGDDAO | |
| SCHEMBL7413639 | 0.78 | PDPK1 (0.42) | PDPK1NAPRTALDH1A1KDM4EHPGD | |
| SCHEMBL19350248 | 0.75 | CXCR2 (0.39) | NAPRTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7413081 | 0.73 | PDPK1 (0.39) | PDPK1NAPRTTSHRTYK2PARP1 | |
| SCHEMBL4783577 | 0.73 | — | — | |
| SCHEMBL82637 | 0.72 | NAPRT (0.67) | PDPK1NAPRTALDH1A1KDM4EHPGD | |
| SCHEMBL3424158 | 0.71 | ERN1 (0.54) | ALDH1A1KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5892029-A | HIGHLY EFFECTIVE UPON BOTH INJECTION AND ORAL ADMINISTRATION. | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-04-06 | — | — | US | disclosed |