Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.67 |
| ▸ | TYK2 | P29597 | 1/20 | 0.58 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30935942 | 0.98 | NAPRT (0.64) | NAPRTTYK2AURKADAOAURKB | |
| Formic Acid SCHEMBL30227578 | 0.92 | NAPRT (0.58) | NAPRTTYK2AURKADAOAURKB | |
| Anthranilamide SCHEMBL5170575 | 0.89 | AURKA (0.55) | NAPRTTYK2AURKADAOAURKB | |
| Thiophene SCHEMBL11983176 | 0.89 | NAPRT (0.55) | NAPRTTYK2AURKADAOAURKB | |
| SCHEMBL425117 | 0.82 | NAPRT (0.72) | NAPRTTYK2AURKADAOAURKB | |
| SCHEMBL8193694 | 0.82 | NAPRT (0.72) | NAPRTTYK2AURKADAOAURKB | |
| SCHEMBL5681688 | 0.81 | ALDH1A1 (0.71) | NAPRTTYK2AURKAPDPK1PARP1 | |
| SCHEMBL1315187 | 0.81 | NAPRT (0.59) | NAPRTTYK2AURKADAOAURKB | |
| SCHEMBL5943030 | 0.81 | NAPRT (0.59) | NAPRTTYK2AURKADAOAURKB | |
| SCHEMBL440492 | 0.80 | NAPRT (1.00) | NAPRTTYK2AURKADAOAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 830 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619407-A1 | PYRIDONE AND PYRIMIDINONE INHIBITORS OF HEMATOPOIETIC PROGENITOR KINASE 1 | Curadev Pharma Ltd (GB) | 2025-09-24 | — | — | EP | claimed |
| US-20250282794-A1 | PYRIDONE AND PYRIMIDINONE INHIBITORS OF HEMATOPOIETIC PROGENITOR KINASE 1 | CURADEV PHARMA LTD (GB) | 2025-09-11 | — | — | US | claimed |
| EP-4573085-A1 | SUBSTITUTED PYRIDINONE COMPOUNDS AS CBL-B INHIBITORS | Glenmark Pharmaceuticals Limited (IN) | 2025-06-25 | — | — | EP | claimed |
| EP-3778608-B1 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USE THEREOF | JIAXING ANDICON BIOTECH CO LTD (CN) | 2025-06-18 | — | — | EP | claimed |
| CN-119698278-A | Small molecule modulators of alveolar type 2 cell proliferation for the treatment of pulmonary diseases | 斯克里普斯研究学院 | 2025-03-25 | — | — | CN | claimed |
| CN-119546587-A | Substituted pyridone compounds as CBL-B inhibitors | 格兰玛克制药有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-119403787-A | 3- (Sulfonyl or iminosulfonyl) prop-2-en-1-yl ] -2-oxo-1, 2-dihydropyridine-3-carboxamide derivatives | 福临德治疗公司 | 2025-02-07 | — | — | CN | claimed |
| US-20240293386-A1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR | LG CHEM, LTD. (KR) | 2024-09-05 | — | — | US | claimed |
| WO-2024105363-A1 | PYRIDONE AND PYRIMIDINONE INHIBITORS OF HEMATOPOIETIC PROGENITOR KINASE 1 | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | claimed |
| EP-3762392-B1 | THIENOPYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | WELLMARKER BIO CO LTD (KR) | 2024-05-15 | — | — | EP | claimed |
| EP-2376080-A1 | SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES | Shionogi&Co., Ltd. (JP) | 2011-10-19 | — | — | EP | claimed |
| CN-101215261-B | Method for synthesizing of 2-oxo-3-pyridine formic acid ester and derivatives thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2011-09-07 | — | — | CN | claimed |
| WO-2011067184-A1 | 3- (4, 5 -DIHYDROISOXAZOL- 5 -YL) BENZOYLPYRAZOLE COMPOUNDS AND MIXTURES THEREOF WITH SAFENERS | BASF SE (DE) | 2011-06-09 | — | — | WO | claimed |
| WO-2010068253-A1 | SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES | SHIONOGI & CO., LTD. (JP) | 2010-06-17 | — | — | WO | claimed |
| CN-101215261-A | Method for synthesizing of 2-oxo-3-pyridine formic acid ester and derivatives thereof | NANJING UNIVERSITY OF TECHNOLOGY (CN) | 2008-07-09 | — | — | CN | claimed |
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | ASTEX TECHNOLOGY, INC. (GB) | 2006-06-22 | — | — | US | claimed |
| JP-2006500348-A | — | — | 2006-01-05 | — | — | JP | claimed |
| EP-1534685-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | Astex Technology Limited (GB) | 2005-06-01 | — | — | EP | claimed |
| WO-2004014864-A1 | 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS CYCLIN DEPENDENT KINASES (CDK) INHIBITORS | ASTEX TECHNOLOGY LIMITED (GB) | 2004-02-19 | — | — | WO | claimed |
| WO-2001077078-A1 | NOVEL PYRIDONES AND THEIR USE AS MODULATORS OF SERINE HYDROLASE ENZYMES | DALHOUSIE UNIVERSITY (CA) | 2001-10-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250282794-A1 | PYRIDONE AND PYRIMIDINONE INHIBITORS OF HEMATOPOIETIC PROGENITOR KINASE 1 | PDXK, PGK1, CMPK1 | NAPRT 892/4885TYK2 227/4885AURKA 418/4885 |
| US-20060135589-A1 | 1h-Indazole-3-carboxamide compounds as cyclin dependent kinase (cdk) inhibitors | CCNC, CDK1, CDK7 | NAPRT 283/4885TYK2 66/4885AURKA 659/4885 |
| US-20240293386-A1 | NOVEL COMPOUND AS PROTEIN KINASE INHIBITOR | MAP3K20, SBK3, MAPKAPK2 | NAPRT 1807/4885TYK2 646/4885AURKA 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.