SCHEMBL8469644

SCHEMBL8469644

CCCCCCC(C)C1C(=O)NC(=O)C1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD1 P17405 3/20 0.35
PTPN1 P18031 1/20 0.35
CCR2 P41597 1/20 0.34
PRKCD Q05655 4/20 0.33
DAGLA Q9Y4D2 1/20 0.33
NAAA Q02083 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
HLCS P50747 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5617212 0.82 DAGLA (0.35) SMPD1PTPN1CCR2PRKCDDAGLA
SCHEMBL5617419 0.81 DAGLA (0.38) SMPD1PTPN1CCR2PRKCDDAGLA
SCHEMBL13522264 0.73 DAGLA (0.39) SMPD1PTPN1DAGLANAAAADH1B
SCHEMBL6381411 0.72 LMNA (0.42) PTPN1CCR2PRKCDDAGLAGPR84
SCHEMBL22300037 0.69 KDM4E (0.32) KDM4EMEN1ALDH1A1MAPTPKM
SCHEMBL22085274 0.69 ALDH1A1 (0.41) CCR2PRKCDDAGLAKDM4EALDH1A1
SCHEMBL5617415 0.69 ALDH1A1 (0.41) CCR2PRKCDDAGLAKDM4EALDH1A1
SCHEMBL6077962 0.69 ALDH1A1 (0.41) CCR2PRKCDDAGLAKDM4EALDH1A1
SCHEMBL6078384 0.69 ALDH1A1 (0.41) CCR2PRKCDDAGLAKDM4EALDH1A1
SCHEMBL19161941 0.69 TSHR (0.47) PTPN1CCR2PRKCDDAGLAGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
EP-0448207-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1993-12-15 EP disclosed
US-5225093-A Metal free ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-07-06 US disclosed
US-5176840-A Succinimide ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-01-05 US disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed
EP-0448207-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-09-25 EP disclosed