Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469650 | 0.92 | MAPT (0.42) | MTNR1AMTNR1BMAPTTP53POLB | |
| SCHEMBL8469409 | 0.85 | MAPT (0.42) | MTNR1AMTNR1BMAPTTP53SMN1; SMN2 | |
| SCHEMBL7388946 | 0.81 | ANO1 (0.45) | MTNR1AMTNR1BMAPTPOLBCNR1 | |
| SCHEMBL7392563 | 0.81 | MTNR1A (0.47) | MTNR1AMTNR1BMAPTTP53POLB | |
| SCHEMBL8469654 | 0.80 | MTNR1A (0.45) | MTNR1AMTNR1BMAPTTP53POLB | |
| SCHEMBL7384691 | 0.79 | KDM4E (0.55) | MAPTTP53 | |
| SCHEMBL8469412 | 0.79 | KDM4E (0.42) | MTNR1AMTNR1BMAPTTP53CYP2C9 | |
| SCHEMBL7392060 | 0.79 | MTNR1A (0.48) | MTNR1AMTNR1BMAPTPOLBCNR1 | |
| SCHEMBL7392062 | 0.73 | CYP2C9 (0.45) | MTNR1AMTNR1BMAPTTP53POLB | |
| SCHEMBL5227728 | 0.73 | SLC22A12 (0.54) | MAPTCNR1CNR2CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962695-A | ANTICOAGULANT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5866577-A | AN ANTICOAGULANT AGENT | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-02-02 | — | — | US | disclosed |