Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227159 | 0.88 | EYA3 (0.66) | SLC22A12CYP2C9NR1H4KDM5AKDM7A | |
| SCHEMBL5225465 | 0.88 | SLC22A12 (0.52) | SLC22A12CYP2C9EYA3CYP3A4MAPT | |
| SCHEMBL5672664 | 0.87 | SLC22A12 (0.51) | SLC22A12CYP2C9CYP3A4MAPTALOX15 | |
| SCHEMBL5227261 | 0.86 | ESR1 (0.70) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL5225391 | 0.85 | NR1H4 (0.60) | SLC22A12CYP2C9NR1H4KDM5AKDM7A | |
| SCHEMBL15488929 | 0.85 | SLC22A12 (0.58) | SLC22A12CYP2C9NR1H4KDM5AKDM7A | |
| SCHEMBL5020569 | 0.85 | SLC22A12 (0.68) | SLC22A12CYP2C9NR1H4KDM5AKDM7A | |
| Oxalic Acid SCHEMBL5674664 | 0.84 | ESR1 (0.67) | ESR1PGRCHRM2HTR1AADRA2A | |
| SCHEMBL5672649 | 0.84 | SLC22A12 (0.57) | SLC22A12CYP2C9ESR1PGRCHRM2 | |
| SCHEMBL11823752 | 0.84 | SLC22A12 (0.57) | SLC22A12CYP2C9NR1H4KDM5AKDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315710-B1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-04-25 | — | — | EP | disclosed |
| US-7148240-B2 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI-AVENTIS (FR) | 2006-12-12 | — | — | US | disclosed |
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | SANOFI (FR) | 2004-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040010011-A1 | Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same | ABAT, TNNT2, BCAT1 | SLC22A12 2161/4885CYP2C9 47/4885NR1H4 2001/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.