Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30169464 | 1.00 | ACVR1 (0.52) | ACVR1JAK2JAK1KDM4ERAB9A | |
| SCHEMBL17262978 | 0.89 | ACVR1 (0.57) | ACVR1KDM4ERAB9AHSD17B10NPC1 | |
| SCHEMBL31462148 | 0.89 | ACVR1 (0.57) | ACVR1KDM4ERAB9AHSD17B10NPC1 | |
| SCHEMBL31462149 | 0.89 | ACVR1 (0.57) | ACVR1KDM4ERAB9AHSD17B10NPC1 | |
| SCHEMBL29229455 | 0.86 | ACVR1 (0.62) | ACVR1KDM4ERAB9AHSD17B10NPC1 | |
| SCHEMBL29229460 | 0.86 | ACVR1 (0.65) | ACVR1KDM4ERAB9AHSD17B10NPC1 | |
| SCHEMBL29229450 | 0.85 | ACVR1 (0.67) | ACVR1KDM4ERAB9AHSD17B10NPC1 | |
| SCHEMBL29229517 | 0.85 | ACVR1 (0.67) | ACVR1KDM4ERAB9AHSD17B10NPC1 | |
| SCHEMBL23518636 | 0.83 | ACVR1 (0.51) | ACVR1KDM4ERAB9AHSD17B10NPC1 | |
| SCHEMBL16333798 | 0.83 | ACVR1 (0.51) | ACVR1KDM4ERAB9AHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11228569-A | — | — | None | — | — | JP | disclosed |
| US-11535597-B2 | Photoreactive ligands and uses thereof | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-12-27 | — | — | US | disclosed |
| US-20200071277-A1 | PHOTOREACTIVE LIGANDS AND USES THEREOF | THE SCRIPPS RESEARCH INSTITUTE | 2020-03-05 | — | — | US | disclosed |
| JP-H11228569-A | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME | JAPAN TOBACCO INC | 1999-08-24 | — | — | JP | disclosed |
| US-4166117-A | HYPOTENSIVES | SCIENCE UNION ET CIE (FR) | 1979-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11535597-B2 | Photoreactive ligands and uses thereof | CLTB, CRYAB, CRYAA | ACVR1 4490/4885JAK2 3776/4885JAK1 4278/4885 |
| US-20200071277-A1 | PHOTOREACTIVE LIGANDS AND USES THEREOF | CLTB, CRYAB, CRYAA | ACVR1 4490/4885JAK2 3776/4885JAK1 4278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.