Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.38 |
| ▸ | HTR6 | P50406 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8470211 | 0.83 | BRD4 (0.35) | BRD4HTR6PDPK1PTPN11DRD2 | |
| SCHEMBL13505045 | 0.82 | HTR6 (0.45) | BRD4HTR6MEN1KMT2ADRD2 | |
| SCHEMBL3352661 | 0.81 | PDPK1 (0.43) | BRD4HTR6MEN1KMT2APDPK1 | |
| SCHEMBL13504975 | 0.80 | BRD4 (0.38) | BRD4HTR6PTPN11DRD2HTR2A | |
| SCHEMBL13504982 | 0.78 | BRD4 (0.36) | BRD4HTR6PDPK1PTPN11DRD2 | |
| SCHEMBL8480893 | 0.78 | BRD4 (0.38) | BRD4HTR6MEN1KMT2APDPK1 | |
| SCHEMBL13538989 | 0.75 | BRD4 (0.37) | BRD4HTR6MEN1KMT2APDPK1 | |
| SCHEMBL13505027 | 0.74 | PIK3CD (0.38) | BRD4HTR6MEN1KMT2APDPK1 | |
| SCHEMBL3355006 | 0.73 | PIK3CD (0.46) | HTR6MEN1KMT2AALDH1A1 | |
| SCHEMBL3347328 | 0.72 | HTR6 (0.38) | BRD4HTR6MEN1KMT2APDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1749829-B1 | JNK inhibitors | EISAI R&D MAN CO LTD (JP) | 2010-11-03 | — | — | EP | disclosed |