Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KAT7 | O95251 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919209 | 0.83 | TSHR (0.36) | L3MBTL1CA1CA2CA4CA9 | |
| SCHEMBL11077242 | 0.82 | L3MBTL1 (0.37) | L3MBTL1GAACA1CA2CA4 | |
| SCHEMBL8860260 | 0.81 | CA1 (0.34) | CA1CA2CA4CA9MAPT | |
| SCHEMBL1128093 | 0.79 | ITGB3 (0.41) | L3MBTL1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL28435066 | 0.77 | L3MBTL1 (0.33) | L3MBTL1CA1CA2CA4CA9 | |
| SCHEMBL1251228 | 0.77 | CA1 (0.40) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL782154 | 0.77 | TAAR1 (0.31) | — | |
| SCHEMBL3834227 | 0.77 | CA1 (0.40) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL6364461 | 0.77 | TAAR1 (0.31) | — | |
| Hydrazine SCHEMBL8553287 | 0.75 | TAAR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0892789-A1 | IRREVERSIBLE INHIBITORS OF TYROSINE KINASES | WARNER-LAMBERT COMPANY (US) | 1999-01-27 | — | — | EP | claimed |
| WO-1997038983-A1 | IRREVERSIBLE INHIBITORS OF TYROSINE KINASES | WARNER-LAMBERT COMPANY (US) | 1997-10-23 | — | — | WO | claimed |