SCHEMBL847003

SCHEMBL847003

CCCCC(N)(N)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 6/20 0.44
KCNN4 O15554 3/20 0.43
TAAR1 Q96RJ0 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
SIGMAR1 Q99720 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28193226 0.94 SCN5A (0.42) KIF11KCNN4TAAR1SIGMAR1
SCHEMBL28338666 0.92 SCN5A (0.44) KIF11KCNN4SIGMAR1
SCHEMBL28340947 0.92 SCN5A (0.44) KIF11KCNN4SIGMAR1
SCHEMBL28306597 0.92 SCN5A (0.44) KIF11KCNN4SIGMAR1
SCHEMBL29288489 0.92 SCN5A (0.44) KIF11KCNN4SIGMAR1
SCHEMBL9756593 0.86 KCNN4 (0.46) KIF11KCNN4TAAR1
Ammonia Solution, Strong SCHEMBL7144895 0.84 KCNN4 (0.45) KIF11KCNN4TAAR1SIGMAR1
SCHEMBL10384482 0.84 KIF11 (0.45) KIF11KCNN4TAAR1ESR1ESR2
SCHEMBL1261574 0.83 KIF11 (0.44) KIF11KCNN4TAAR1ESR1ESR2
SCHEMBL9426651 0.81 TAAR1 (0.43) KIF11KCNN4TAAR1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2951222-B1 LOW FREE MDI PREPOLYMERS FOR ROTATIONAL CASTING CHEMTURA CORP (US) 2016-09-21 EP claimed
EP-0202557-B1 PROCESS FOR PRODUCING MONOTERTIARY BUTYL TOLUENEDIAMINE AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-09-11 EP claimed
EP-0178583-B1 POLYURETHANE SYSTEMS USING MONOTERTIARY-ALKYLTOLUENEDIAMINE AS A CROSS LINKER AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-05-31 EP claimed
US-4816543-A REACTIN INJECTION MOLDING MATERIALS AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-03-28 US claimed
EP-0202557-A2 Process for producing monotertiary butyl toluenediamine AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-11-26 EP claimed
WO-2022230878-A1 BELT FOR PAPERMAKING AND METHOD FOR PRODUCING BELT FOR PAPERMAKING イチカワ株式会社 2022-11-03 WO disclosed
CN-109438797-A Novel modified asphalt glue 耿佃勇 2019-03-08 CN disclosed
CN-103140532-B Epoxy resin adduct and thermosets thereof Blue Cube Intellectual Property Co.,Ltd. (US) 2016-05-04 CN disclosed
EP-2432815-A2 POLYUREA WHICH CAN BE PRODUCED FROM TWO POLYETHERAMINES AND A PREPOLYMER BASF SE (DE) 2012-03-28 EP disclosed
EP-2291426-A1 ADDUCTS OF EPOXY RESINS DERIVED FROM ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME Dow Global Technologies Inc. (US) 2011-03-09 EP disclosed
EP-2283058-A1 EPOXY RESINS DERIVED FROM SEED OIL BASED ALKANOLAMIDES AND A PROCESS FOR PREPARING THE SAME Dow Global Technologies Inc. (US) 2011-02-16 EP disclosed
WO-2010133630-A2 POLYUREA WHICH CAN BE PRODUCED FROM TWO POLYETHERAMINES AND A PREPOLYMER BASF SE (DE) 2010-11-25 WO disclosed
US-4745223-A CHAIN EXTENDERS FOR POLYUREAS AND POLYURETHANES AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-05-17 US disclosed
US-4740620-A HIGH SELECTIVITY TO THE ORTHO POSITION AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-04-26 US disclosed
EP-0255930-A2 Polyurethane foams incorporating alkoxylated aromatic diamine and acetylenic glycol AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-02-17 EP disclosed
EP-0226781-A1 Alkylation of aromatic amines in the presence of acidic, crystalline molecular sieves AIR PRODUCTS AND CHEMICALS, INC. (US) 1987-07-01 EP disclosed
EP-0202557-A2 Process for producing monotertiary butyl toluenediamine AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-11-26 EP disclosed
EP-0202557-A2 Process for producing monotertiary butyl toluenediamine AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-11-26 EP disclosed
EP-0202557-A2 Process for producing monotertiary butyl toluenediamine AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-11-26 EP disclosed
EP-0177916-A1 Mono-tertiary-alkylated toluenediamine and derivatives AIR PRODUCTS AND CHEMICALS, INC. (US) 1986-04-16 EP disclosed