Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7144895

CCCC(N)(N)c1ccccc1.N

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KCNN4 O15554 3/20 0.45
TAAR1 Q96RJ0 2/20 0.41
KIF11 P52732 6/20 0.39
SLC6A2 P23975 1/20 0.37
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
CYP2C19 P33261 1/20 0.35
SCN1A P35498 1/20 0.35
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
SCN2A Q99250 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
SCN3A Q9NY46 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9756593 0.98 KCNN4 (0.46) KCNN4TAAR1KIF11SLC6A2CYP1A2
SCHEMBL847003 0.84 KIF11 (0.44) KCNN4TAAR1KIF11SIGMAR1
SCHEMBL28193226 0.83 SCN5A (0.42) KCNN4TAAR1KIF11SIGMAR1
SCHEMBL157809 0.81 KCNN4 (0.48) KCNN4TAAR1KIF11SLC6A2CYP1A2
SCHEMBL29288489 0.81 SCN5A (0.44) KCNN4KIF11SIGMAR1
SCHEMBL28340947 0.81 SCN5A (0.44) KCNN4KIF11SIGMAR1
SCHEMBL28306597 0.81 SCN5A (0.44) KCNN4KIF11SIGMAR1
SCHEMBL28338666 0.81 SCN5A (0.44) KCNN4KIF11SIGMAR1
SCHEMBL8170446 0.81 MEN1 (0.38) KCNN4CYP1A2LMNARAB9A
Bromide SCHEMBL10687152 0.79 KCNN4 (0.46) KCNN4TAAR1KIF11SLC6A2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1321453-A3 N-(Aminopropyl)-toluenediamines and their use as epoxy curing agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2003-08-13 EP disclosed
EP-1321453-A2 N-(Aminopropyl)-toluenediamines and their use as epoxy curing agents AIR PRODUCTS AND CHEMICALS, INC. (US) 2003-06-25 EP disclosed