Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20671588 | 1.00 | L3MBTL1 (0.56) | L3MBTL1EPAS1MBTD1L3MBTL3SLC18A3 | |
| SCHEMBL24693272 | 1.00 | L3MBTL1 (0.56) | L3MBTL1EPAS1MBTD1L3MBTL3SLC18A3 | |
| SCHEMBL14303784 | 0.94 | L3MBTL1 (0.54) | L3MBTL1EPAS1 | |
| SCHEMBL18882514 | 0.91 | L3MBTL1 (0.50) | L3MBTL1EPAS1MBTD1L3MBTL3 | |
| SCHEMBL24693273 | 0.86 | L3MBTL1 (0.60) | L3MBTL1 | |
| SCHEMBL8291836 | 0.86 | L3MBTL1 (0.60) | L3MBTL1 | |
| SCHEMBL12954573 | 0.84 | L3MBTL1 (0.46) | L3MBTL1EPAS1SLC18A3SIGMAR1 | |
| SCHEMBL12954575 | 0.84 | L3MBTL1 (0.46) | L3MBTL1EPAS1SLC18A3SIGMAR1 | |
| SCHEMBL15989789 | 0.83 | L3MBTL1 (0.42) | L3MBTL1EPAS1 | |
| SCHEMBL3962365 | 0.83 | L3MBTL1 (0.56) | L3MBTL1EPAS1MBTD1L3MBTL3SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4287344-A | N,N-bis-(decahydroquinolyl-N-methyl)imidazolin-2-thiones | SAFAEV ABIDZHAN | 1981-09-01 | — | — | US | claimed |
| WO-2021030620-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| WO-2020150675-A1 | COMPOUNDS AND USES THEREOF | NUVATION BIO INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| WO-2019018583-A1 | 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF | GiraFpharma LLC (US) | 2019-01-24 | — | — | WO | disclosed |
| US-8106046-B2 | Cyclopentathiophene modulators of the glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-01-31 | — | — | US | disclosed |
| US-20110105495-A1 | CYCLOPENTATHIOPHENE MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | BRISTOL-MYERS SQUIBB COMPANY | 2011-05-05 | — | — | US | disclosed |
| EP-0959083-A1 | Process for polymerization of alpha-olefin and alpha-olefin polymer | Grand Polymer Co., Ltd. (JP) | 1999-11-24 | — | — | EP | disclosed |
| US-4500341-A | PREEMERGENCE, POSTEMERGENCE HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-19 | — | — | US | disclosed |
| EP-0014880-B1 | PHENOXYCARBOXYLIC ACID AMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1982-09-22 | — | — | EP | disclosed |
| US-4287344-A | N,N-bis-(decahydroquinolyl-N-methyl)imidazolin-2-thiones | SAFAEV ABIDZHAN | 1981-09-01 | — | — | US | disclosed |
| EP-0014880-A1 | Phenoxycarboxylic acid amides, process for their preparation and their use as herbicides | BAYER AG (DE) | 1980-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105495-A1 | CYCLOPENTATHIOPHENE MODULATORS OF THE GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-kB ACTIVITY AND USE THEREOF | NFKB2, NFKB1, NFRKB | L3MBTL1 2069/4885EPAS1 631/4885MBTD1 481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.