Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424240 | 0.89 | TAAR1 (0.47) | TAAR1 | |
| SCHEMBL23315604 | 0.79 | TYR (0.31) | — | |
| SCHEMBL2312796 | 0.77 | GRIA4 (0.50) | GRIA4PTGS2CHRNB2CHRNA4TAAR1 | |
| SCHEMBL8470432 | 0.76 | GRIA4 (0.46) | GRIA4PTGS2CHRNB2CHRNA4CYP1A2 | |
| SCHEMBL4309371 | 0.73 | APP (0.39) | CYP1A2 | |
| SCHEMBL11609177 | 0.73 | GRIA4 (0.48) | GRIA4PTGS2 | |
| SCHEMBL528539 | 0.73 | CYP1A2 (0.56) | GRIA4PTGS2CYP1A2GAACYP2C9 | |
| SCHEMBL20563823 | 0.73 | CYP1A2 (0.56) | GRIA4PTGS2CYP1A2GAACYP2C9 | |
| SCHEMBL1966503 | 0.73 | KCNJ1 (0.44) | PTGS2CYP1A2GAA | |
| SCHEMBL9572888 | 0.71 | RIPK1 (0.47) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4520193-A | Cephalosporin derivatives | RHONE-POULENC INDUSTRIES (FR) | 1985-05-28 | — | — | US | claimed |
| US-5952497-A | USEFUL IN PEPTIDE, POLYPEPTIDE AND PROTEIN SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) | 1999-09-14 | — | — | US | disclosed |