Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 3/20 | 0.32 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.32 |
| ▸ | RBBP4 | Q09028 | 2/20 | 0.32 |
| ▸ | AEBP2 | Q6ZN18 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613828 | 1.00 | MEN1 (0.34) | MEN1KMT2AEEDSUZ12EZH2 | |
| SCHEMBL8473758 | 0.73 | PTPRC (0.42) | MEN1KMT2AMTNR1AMTNR1BGRM5 | |
| SCHEMBL339504 | 0.70 | MTNR1B (0.36) | MTNR1AMTNR1B | |
| SCHEMBL1516337 | 0.70 | MTNR1B (0.36) | MTNR1AMTNR1B | |
| SCHEMBL339505 | 0.70 | MTNR1B (0.36) | MTNR1AMTNR1B | |
| SCHEMBL2435383 | 0.69 | POLB (0.39) | MEN1KMT2A | |
| SCHEMBL624687 | 0.68 | MEN1 (0.40) | MEN1KMT2AGRM5 | |
| SCHEMBL624686 | 0.68 | MEN1 (0.40) | MEN1KMT2AGRM5 | |
| SCHEMBL29960518 | 0.68 | MEN1 (0.40) | MEN1KMT2AGRM5 | |
| SCHEMBL4685390 | 0.68 | KIF11 (0.41) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948817-A | Polycyclic ethyl alkylamide melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| WO-1998038991-A1 | POLYCYCLIC ETHYL ALKYLAMIDE MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |