Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM3 | Q14832 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.52 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | GCLC | P48506 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471391 | 0.84 | FDPS (0.42) | GRM3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2742758 | 0.83 | CHRM1 (0.58) | GRM3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5060255 | 0.82 | GRM3 (0.82) | GRM3FOLH1NAALAD2 | |
| SCHEMBL15965757 | 0.81 | GCLC (0.57) | GRM3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL5057870 | 0.79 | FOLH1 (0.64) | GRM3CHRM1AKR1A1CHRM3HTR2A | |
| Valproic Acid SCHEMBL27811699 | 0.76 | CHRM1 (0.80) | GRM3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL9715079 | 0.75 | CHRM1 (0.52) | GRM3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL11959173 | 0.75 | GCLC (0.54) | GRM3CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL14927201 | 0.75 | GCLC (0.82) | GCLCFOLH1GRIK1SLC1A3SLC1A2 | |
| SCHEMBL14380091 | 0.73 | CHRM1 (0.54) | GRM3CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999033847-A9 | PHOSPHINIC ALKANOIC ACID DERIVATIVES | GUILFORD PHARM INC (US) | 1999-09-23 | — | — | WO | disclosed |